4-hexyloxy-2,3,5,6-tetrafluorophenylbis(trifluoromethanesulfonyl)methane

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 4-hexyloxy-2,3,5,6-tetrafluorophenylbis(trifluoromethanesulfonyl)methane
• 英文别名: (4-hexyloxy-2,3,5,6-tetrafluorophenyl)bis(triflyl)methane；alpha,alpha-Bis(trifluoromethylsulfonyl)-4-(hexyloxy)-2,3,5,6-tetrafluorotoluene；1-[bis(trifluoromethylsulfonyl)methyl]-2,3,5,6-tetrafluoro-4-hexoxybenzene
• 化学式: C₁₅H₁₄F₁₀O₅S₂
• 分子量: 528.389
• InChiKey: ILIDNQQDMLBNCZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  32
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  94.3
• 氢给体数：
  0
• 氢受体数：
  15

反应信息

• 作为产物：
  描述：

  lithium (pentafluorophenyl)bis(triflyl)methanide 、 正己醇 在 吡啶 、 sodium hydride 作用下， 以83%的产率得到4-hexyloxy-2,3,5,6-tetrafluorophenylbis(trifluoromethanesulfonyl)methane
  参考文献：
  名称：

  Facile Synthesis of Aryl- and Alkyl-bis(trifluoromethylsulfonyl)methanes

  摘要：

  通过将相应的苄基卤化物与三氟甲烷亚硫酸钠反应，然后再与三氟甲磺酸酐反应，合成了多种芳香基双(三氟甲磺酰)甲烷 (1)。此外，当1中的芳基是五氟苯基时，芳基的亲核性对位取代反应可以通过烷基锂和烷氧化钠实现。这一反应对于设计新型布朗斯特酸具有实用价值。

  DOI：

  10.1246/bcsj.78.1401

文献信息

• A Fluorous Super Brønsted Acid Catalyst: Application to Fluorous Catalysis without Fluorous Solvents
  作者：Hisashi Yamamoto、Kazuaki Ishihara、Aiko Hasegawa

  DOI：10.1055/s-2002-32965

  日期：——

  The preparation of a fluorous super Bronsted acid catalyst, 4-(1H,1H-perfluorotetradecanoxy)-2,3,5,6-tetrafluorophenylbis(trifluoromethanesulfonyl)methane (3d), is described. The fluorous catalyst 3d can be recycled by using liquid/solid phase separation without fluorous solvents. A perfluorocarbon solvent is not essential for fluorous biphasic catalysis.

  描述了含氟超布朗斯台德酸催化剂 4-(1H,1H-全氟十四烷氧基)-2,3,5,6-四氟苯基双(三氟甲磺酰基)甲烷 (3d) 的制备。含氟催化剂3d可以通过使用液/固相分离而无需含氟溶剂来回收。全氟化碳溶剂对于含氟双相催化不是必需的。
• Arylbis(perfluoroalkylsulfonyl) methane and metallic salt thereof and methods for producing the same
  申请人：——

  公开号：US20040030192A1

  公开（公告）日：2004-02-12

  The present invention provides a method for producing various types of arylbis(perfluoroalkylsulfonyl)methane having a bulky aryl group and an electron-accepting aryl group in which synthesis was conventionally considered to be difficult, at high efficiency; a novel arylbis(perfluoroalkylsulfonyl)methane that can be widely applied to asymmertric catalyst, various types of functional materials and the like; and a metallic salt thereof. In addition, excellent catalysts are also provided. An aryl halomethane is reacted with a sodium trifluoromethane sulfinate, the arylmethyl triflone produced thereby is reacted with a t-BuLi and the like, the lithium salt of the arylmethyl triflone obtained is reacted with a trifluoromethane sulfonic acid anhydride, and an arylbis(trifluoromethylsulfony)methane such as pentafluorophenylbis(triflyl)methane, {4-(pentafluorophenyl)-2,3,5,6-tetrafluorophenyl}bis(triflyl)methane and the like are obtained at a high yield.

  本发明提供了一种高效率生产具有笨重芳基和电子受体芳基的各种类型的芳基双(全氟烷基磺酰)甲烷的方法，该合成在传统上被认为是困难的；一种可以广泛应用于不对称催化剂、各种类型的功能材料等的新型芳基双(全氟烷基磺酰)甲烷；以及其金属盐。此外，还提供了优秀的催化剂。将芳基卤代甲烷与三氟甲烷磺酸钠反应，所产生的芳基甲基三氟甲烷磺酸盐与t-BuLi等反应，得到芳基甲基三氟甲烷磺酸锂盐，再与三氟甲烷磺酸酐反应，得到芳基双(三氟甲烷基磺酰)甲烷，如五氟苯基双(三氟甲烷基磺酰)甲烷、4-(五氟苯基)-2,3,5,6-四氟苯基双(三氟甲烷基磺酰)甲烷等，收率高。
• Arylbis (perfluoroalkylsulfonyl)methane and metallic salt thereof, and methods for producing the same
  申请人：Ishihara Kazuaki

  公开号：US20050070741A1

  公开（公告）日：2005-03-31

  The present invention provides a method for producing various types of arylbis(perfluoroalkylsulfonyl)methane having a bulky aryl group and an electron-accepting aryl group in which synthesis was conventionally considered to be difficult, at high efficiency; a novel arylbis(perfluoroalkylsulfonyl)methane that can be widely applied to asymmertric catalyst, various types of functional materials and the like; and a metallic salt thereof. In addition, excellent catalysts are also provided. An aryl halomethane is reacted with a sodium trifluoromethane sulfinate, the arylmethyl triflone produced thereby is reacted with a t-BuLi and the like, the lithium salt of the arylmethyl triflone obtained is reacted with a trifluoromethane sulfonic acid anhydride, and an arylbis (trifluoromethylsulfony)methane such as pentafluorophenylbis(triflyl)methane, 4-(pentafluorophenyl)-2,3,5,6-tetrafluorophenyl}bis(triflyl)methane and the like are obtained at a high yield.

  本发明提供了一种高效生产具有笨重芳基和电子受体芳基的各种类型的芳基双(全氟烷基磺酰基)甲烷的方法，该合成通常被认为很难；一种新型的芳基双(全氟烷基磺酰基)甲烷，可广泛应用于不对称催化剂、各种类型的功能材料等；以及其金属盐。此外，还提供了优良的催化剂。将芳基卤代甲烷与三氟甲烷磺酰酸钠反应，得到芳基甲基三氟甲烷磺酰酸盐，再与t-BuLi等反应，得到芳基甲基三氟甲烷磺酸锂盐，最后与三氟甲烷磺酸酐反应，得到高产率的芳基双(三氟甲基磺酰基)甲烷，如五氟苯基双(三氟甲基磺酰基)甲烷、4-(五氟苯基)-2,3,5,6-四氟苯基}双(三氟甲基磺酰基)甲烷等。
• Arylbis(perfluoroalkylsulfonyl) methane and metallic salt thereof, and methods for producing the same
  申请人：Japan Science and Technology Corporation

  公开号：US07193113B2

  公开（公告）日：2007-03-20

  The present invention provides a method for producing various types of arylbis(perfluoroalkylsulfonyl)methane having a bulky aryl group and an electron-accepting aryl group in which synthesis was conventionally considered to be difficult, at high efficiency; a novel arylbis(perfluoroalkylsulfonyl)methane that can be widely applied to asymmertric catalyst, various types of functional materials and the like; and a metallic salt thereof. In addition, excellent catalysts are also provided. An aryl halomethane is reacted with a sodium trifluoromethane sulfinate, the arylmethyl triflone produced thereby is reacted with a t-BuLi and the like, the lithium salt of the arylmethyl triflone obtained is reacted with a trifluoromethane sulfonic acid anhydride, and an arylbis(trifluoromethylsulfony)methane such as pentafluorophenylbis(triflyl)methane, 4-(pentafluorophenyl)-2,3,5,6-tetrafluorophenyl}bis(triflyl)methane and the like are obtained at a high yield.

  本发明提供了一种高效生产具有笨重芳基和电子受体芳基的各种芳基双(全氟烷基磺酰基)甲烷的方法，其合成在传统上被认为是困难的；一种新型的芳基双(全氟烷基磺酰基)甲烷，可广泛应用于不对称催化剂、各种功能材料等；以及其金属盐。此外，还提供了优秀的催化剂。将芳基卤代甲烷与三氟甲烷磺酰亚胺钠反应，生成的芳基甲基三氟甲烷磺酰酸盐与t-BuLi等反应，得到芳基甲基三氟甲烷磺酸锂盐，然后与三氟甲烷磺酸酐反应，得到高产率的芳基双(三氟甲基磺酰基)甲烷，如五氟苯基双(三氟乙酰基)甲烷、4-(五氟苯基)-2,3,5,6-四氟苯基}双(三氟乙酰基)甲烷等。
• A CATALYST FOR HOMOPOLYMERIZING AND COPOLYMERIZING PROPYLENE AND ITS PREPARATION AND USE
  申请人：Petrochina Company Limited

  公开号：EP2345675A1

  公开（公告）日：2011-07-20

  A catalyst for homopolymerizing and copolymerizing propylene and its preparation and use. The catalyst component includes titanium compound containing at least one Ti-halogen bond and at least two kinds of electron donor compounds A and B supported on MgCl2.nROH adduct, wherein the electron donor compound A is a compound of formula (I), the electron donor compound B is ester or ether compound; the molar ratio between compound A and compound B is 0.1-5; the molar ratio between the total amounts of the two kinds of electron donors and MgCl2.nROH is 0.01-1, based on the amount of MgCl2.nROH; and the molar ration between the titanium compound containing Ti-halogen bond and MgCl2.nROH is 1-200. The catalyst has high activity high stereospecificity and good copolymerization performance. In addition, the morphology of the polymer obtained therefrom is good.

  一种用于均聚和共聚丙烯的催化剂及其制备和使用方法。催化剂组分包括含有至少一个钛卤键的钛化合物和至少两种支撑在 MgCl2.nROH 加合物上的电子供体化合物 A 和 B，其中电子供体化合物 A 为式（I）化合物，电子供体化合物 B 为酯或醚化合物；化合物 A 和化合物 B 的摩尔比为 0.1-5；以MgCl2.nROH的量计，两种电子供体与MgCl2.nROH总量的摩尔比为0.01-1；含Ti-卤素键的钛化合物与MgCl2.nROH的摩尔比为1-200。该催化剂具有高活性、高立体特异性和良好的共聚性能。此外，由此获得的聚合物的形态也很好。