2-[2-(2-methoxyethoxy)ethoxy]benzaldehyde

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-[2-(2-methoxyethoxy)ethoxy]benzaldehyde
• 化学式: C₁₂H₁₆O₄
• 分子量: 224.257
• InChiKey: ROQKINZEVKZSGI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  16
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-[2-(2-methoxyethoxy)ethoxy]benzaldehyde 在 盐酸 、 氢氧化钾 、 盐酸羟胺 、 sodium cyanoborohydride 作用下， 以 甲醇 、 水 、 苯 为溶剂， 反应 4.0h， 生成 (E)-N-(2-(2-(2-methoxyethoxy)ethoxy)benzyl)-1-(pyren-1-yl)methanimine oxide
  参考文献：
  名称：

  Selective complexation of metals with isoxazolidine-containing fluorophores

  摘要：

  A series of 1,3-dipolar cycloaddition products of functionalized nitrones with 1,3-propene sultone and maleimide was synthesized through a multi-step scheme. Their fluorescent response to different metal ions was examined. Selective quenching, of the fluorescent materials by Cu(II) Fe(III) and Ru(III) in acetonitrile was demonstrated, providing access to new chemosensor design for selected transition metals. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2004.10.171

文献信息

• New thiazolothiazole derivatives as fluorescent chemosensors for Cr3+ and Al3+
  作者：Ji Young Jung、Su Jung Han、Jihyun Chun、Chongmok Lee、Juyoung Yoon

  DOI：10.1016/j.dyepig.2012.02.005

  日期：2012.9

  Two new 2,5-diarylthiazolo[5,4-d]thiazole derivatives bearing ethylene oxide moieties were synthesized. Their photophysical and electrochemical properties as well as binding properties towards various metal ions were examined. Thiazole derivative 1 showed large fluorescent enhancements with Cr3+ and Al3+. On the other hand, thiazole derivative 2 displayed a selective fluorescent change with Cr3+ among the metal ions examined. As far as we are aware of, these are the first examples of thiazolothiazole derivatives as fluorescent chemosensors for metal ions. (C) 2012 Elsevier Ltd. All rights reserved.