2-methoxybenzaldehyde N-(4-methylphenyl)thiosemicarbazone

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-methoxybenzaldehyde N-(4-methylphenyl)thiosemicarbazone
• 英文别名: 1-[(E)-(2-methoxyphenyl)methylideneamino]-3-(4-methylphenyl)thiourea
• 化学式: C₁₆H₁₇N₃OS
• 分子量: 299.4
• InChiKey: LXZUFBOYVCDYGK-GZTJUZNOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  77.7
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• CYTOTOXIC COMPOUNDS
  申请人：Scaife Robin

  公开号：US20120238604A1

  公开（公告）日：2012-09-20

  The present invention relates to a compound of general formula (I) or a pharmaceutically acceptable salt or solvate or thereof. In particular, the present invention relates to a method treating diseases involving cell proliferation, migration, apoptosis, or adhesion, comprising administering to a human or non-human mammalian patient an effective amount of a compound of general formula (I) or a pharmaceutically acceptable salt or solvate or thereof.
• [EN] CYTOTOXIC COMPOUNDS<br/>[FR] COMPOSÉS CYTOTOXIQUES
  申请人：MOLECULAR DISCOVERY SYSTEMS

  公开号：WO2011026193A1

  公开（公告）日：2011-03-10

  The present invention relates to a compound of general formula (I) or a pharmaceutically acceptable salt or solvate or thereof. In particular, the present invention relates to a method treating diseases involving cell proliferation, migration, apoptosis, or adhesion, comprising administering to a human or non-human mammalian patient an effective amount of a compound of general formula (I) or a pharmaceutically acceptable salt or solvate or thereof.