4-pentenoic acid sodium salt

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-pentenoic acid sodium salt
• 英文别名: sodium 4-pentenoate；Sodium;pent-4-enoate
• 化学式: C₅H₇O₂*Na
• 分子量: 122.099
• InChiKey: WNAJIILVQHSJSC-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -3.29
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  40.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-pentenoic acid sodium salt 在 1-[4-N,N-bis(carboxylatomethyl)aminophenyltelluro]-3-phenoxypropane disodium salt 双氧水 、 sodium iodide 作用下， 以 phosphate buffer 为溶剂， 反应 1.0h， 以88%的产率得到5-iodomethyl-dihydro-furan-2-one
  参考文献：
  名称：

  Iodination of Organic Substrates with Halide Salts and H₂O₂ Using an Organotelluride Catalyst

  摘要：

  [figure: see text] Organotelluride 1 is a water-soluble catalyst for the oxidation of iodide with hydrogen peroxide in pH 6 phosphate buffer. In two-phase systems, organic substrates are efficiently iodinated using 0.8 mol % of catalyst. Water-soluble substrates are iodinated without an organic cosolvent.

  DOI：

  10.1021/ol0068142

文献信息

• Synthesis of Allyl Acetates via Palladium-Catalysed Functionalisation of Allenes and 1,3-Dienes
  作者：Suren Husinec、Milos Petkovic、Vladimir Savic、Milena Simic

  DOI：10.1055/s-0031-1289658

  日期：2012.2

  π-Allylpalladium intermediates are known to participate efficiently in transformations involving nucleophilic species. Exploring these processes, we have developed a method for the preparation of allyl acetates via palladium-catalysed functionalisation of allenes and 1,3-dienes. Reactions of aryl iodides with either of these two classes of compounds and excess sodium acetate in the presence of Pd(OAc)2

  已知π-烯丙基钯中间体可有效地参与涉及亲核物质的转化。探索这些过程，我们已经开发了一种通过钯催化的丙二烯和1,3-二烯官能化反应制备乙酸烯丙酯的方法。在作为催化体系的Pd（OAc）2和Ph 3 P存在下，芳基碘化物与这两类化合物中的任一种和过量的乙酸钠反应，得到各自的乙酸烯丙酯，产率中等至良好。已经研究了该过程的范围。所描述的方法是用于制备乙酸烯丙酯的合成库的补充，并且尤其可用于合成这种类型的结构复杂的化合物。 乙酸烯丙酯-钯催化-丙二烯-二烯-合成
• Absolute Rate Constants of Alkene Addition Reactions of a Fluorinated Radical in Water
  作者：L. Zhang、W. R. Dolbier,、B. Sheeller、K. U. Ingold

  DOI：10.1021/ja0256010

  日期：2002.6.1

  Absolute rate constants of *R(f)SO(3)(-) radical addition to a series of water-soluble alkenes containing ionic, carboxylate substituents were measured by laser flash photolysis experiments in water. The observed rate constants were all considerably larger than those of structurally similar analogues in a nonpolar organic solvent, with rate factors of 3-9-fold being observed. It is concluded that such

  *R(f)SO(3)(-) 自由基添加到一系列含有离子、羧酸盐取代基的水溶性烯烃的绝对速率常数是通过激光闪光光解实验在水中测量的。观察到的速率常数都比非极性有机溶剂中结构相似的类似物大得多，观察到的速率因子为 3-9 倍。得出的结论是，这种速率提高至少部分源于极性过渡态的稳定性，以通过极性溶剂水将亲电子氟化自由基加成到烯烃上。
• MATTESON, D. S.;MAJUMDAR, D., ORGANOMETALLICS, 1983, 2, N 11, 1529-1535
  作者：MATTESON, D. S.、MAJUMDAR, D.

  DOI：——

  日期：——
• TEULON, JEAN-MARIE
  作者：TEULON, JEAN-MARIE

  DOI：——

  日期：——
• Iodination of Organic Substrates with Halide Salts and H₂O₂ Using an Organotelluride Catalyst
  作者：Michael R. Detty、Donald E. Higgs、Marina I. Nelen

  DOI：10.1021/ol0068142

  日期：2001.2.1

  [figure: see text] Organotelluride 1 is a water-soluble catalyst for the oxidation of iodide with hydrogen peroxide in pH 6 phosphate buffer. In two-phase systems, organic substrates are efficiently iodinated using 0.8 mol % of catalyst. Water-soluble substrates are iodinated without an organic cosolvent.