9-Methyl-3-[4-(trifluoromethoxy)phenyl]-9-azabicyclo[3.3.1]non-2-ene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 9-Methyl-3-[4-(trifluoromethoxy)phenyl]-9-azabicyclo[3.3.1]non-2-ene
• 化学式: C₁₆H₁₈F₃NO
• 分子量: 297.31
• InChiKey: QGCXVJFEWBGIBU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• Novel azabicyclo derivatives and their use
  申请人：——

  公开号：US20010047028A1

  公开（公告）日：2001-11-29

  The present invention relates to 8-azabicyclo[3.2.1]oct-2-ene derivatives in their labelled form. Furthermore, the present invention relates to the use of said derivatives in their labelled or unlabelled form in diagnostic methods, in particular for in vivo receptor imaging (neuroimaging).

  本发明涉及8-氮杂双环[3.2.1]辛-2-烯衍生物及其标记形式。此外，本发明还涉及所述衍生物在其标记或非标记形式中在诊断方法中的使用，特别是用于体内受体成像（神经成像）。
• NOVEL AZABICYCLO DERIVATIVES AND THEIR USE
  申请人：NEUROSEARCH A/S

  公开号：EP1149095A1

  公开（公告）日：2001-10-31
• US6617459B2
  申请人：——

  公开号：US6617459B2

  公开（公告）日：2003-09-09
• [EN] NOVEL AZABICYCLO DERIVATIVES AND THEIR USE<br/>[FR] NOUVEAUX DERIVES D'AZABICYCLO ET LEUR UTILISATION
  申请人：NEUROSEARCH AS

  公开号：WO2000044746A1

  公开（公告）日：2000-08-03

  The present invention relates to 8-azabicyclo[3.2.1]oct-2-ene derivatives in their labelled form. Furthermore, the present invention relates to the use of said derivatives in their labelled or unlabelled form in diagnostic methods, in particular for in vivo receptor imaging (neuroimaging).