N-dodecyl-N,N-dimethylammonium-3-propane sulphonate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: N-dodecyl-N,N-dimethylammonium-3-propane sulphonate
• 英文别名: dodecyl(dimethyl)azanium;propane-1-sulfonate
• 化学式: C17H39NO3S
• 分子量: 337.6
• InChiKey: NYUQKKWCYPVQGE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.99
• 重原子数：
  22
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  70
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME
  申请人：HAYASHIBARA CO., LTD.

  公开号：US20150342854A1

  公开（公告）日：2015-12-03

  The present invention has an object to provide an external dermal composition for anti-ageing, which prevents or improves apparent skin problems such as wrinkles, fine wrinkles, blemishes, and saggings caused by increasing age or ageing; and maintains or improves the barrier function and the hyaluronic acid production in the skin. The object is solved by providing an external dermal composition for anti-ageing, which contains an aqueous medium as a base material and one or more ingredients selected from L-ascorbic acid, derivatives thereof, and their salts as an effective ingredient(s).

  本发明的目的是提供一种用于抗衰老的外用皮肤组成物，该组成物可以预防或改善因年龄增长或衰老引起的皮肤问题，如皱纹、细纹、斑点和下垂，并维持或改善皮肤的屏障功能和透明质酸的产生。本发明通过提供一种外用皮肤组成物来实现该目的，该组成物包含水性介质作为基材料，并含有一种或多种从L-抗坏血酸、其衍生物和它们的盐中选择的成分作为有效成分。
• External dermal composition for anti-ageing and method for producing the same
  申请人：Hayashibara Co., Ltd.

  公开号：US10111822B2

  公开（公告）日：2018-10-30

  The present invention has an object to provide an external dermal composition for anti-ageing, which prevents or improves apparent skin problems such as wrinkles, fine wrinkles, blemishes, and saggings caused by increasing age or ageing; and maintains or improves the barrier function and the hyaluronic acid production in the skin. The object is solved by providing an external dermal composition for anti-ageing, which contains an aqueous medium as a base material and one or more ingredients selected from L-ascorbic acid, derivatives thereof, and their salts as an effective ingredient(s).

  本发明的目的是提供一种用于抗衰老的外用真皮组合物，该组合物可预防或改善因年龄增长或老化引起的皱纹、细小皱纹、斑点和疤痕等明显的皮肤问题，并保持或改善皮肤的屏障功能和透明质酸的生成。本发明的目的是提供一种用于抗衰老的外用皮肤组合物，该组合物含有作为基质材料的水介质和作为有效成分的一种或多种选自 L-抗坏血酸、其衍生物及其盐类的成分。
• Ionic liquids for transdermal drug delivery
  申请人：The Regents of the University of California

  公开号：US10449254B2

  公开（公告）日：2019-10-22

  The compositions and methods described herein are topically applied to the skin with negligible or no skin irritation and can direct or prevent transport through the skin. The compositions contain neat ionic liquids, optionally in combination with a drug to be delivered. In a preferred embodiment, the compositions increase transdermal transport of the drug to be delivered. In some embodiments, the compositions disrupt bacterial biofilms. This is particularly beneficial in the treatment of antibiotic resistant skin infections. In other embodiments, the compositions direct delivery within the skin. In still other embodiments, the compositions prevent transfer of substances through the stratum corneum. The disclosed compositions and methods can be tuned and modified such that they can be used to treat or prevent a variety of different diseases and disorders.

  本文所述的组合物和方法可局部用于皮肤，对皮肤的刺激微乎其微或没有刺激，并可引导或阻止通过皮肤的传输。组合物中含有纯净的离子液体，可选择与待输送的药物结合使用。在一个优选的实施方案中，组合物能增加待递送药物的透皮运输。在某些实施方案中，组合物能破坏细菌生物膜。这对治疗抗生素耐药性皮肤感染尤其有益。在其他实施方案中，组合物能引导皮肤内的给药。在另一些实施方案中，组合物可以防止物质通过角质层转移。所公开的组合物和方法可进行调整和修改，从而可用于治疗或预防各种不同的疾病和失调。
• Process for producing catalysts comprising nanosize metal particles on a porous support, in particular for the gas-phase oxidation of ethylene and acetic acid to give vinyl acetate
  申请人：Celanese Chemical Europe GmbH

  公开号：US20030187294A1

  公开（公告）日：2003-10-02

  The invention relates to a method for producing a catalyst containing one or several metals from the group of metals comprising the subgroups Ib and VIIIb of the periodic table on porous support particles, characterised by a first step in which one or several precursors from the group of compounds of metals from sub-groups Ib and VIIIb of the periodic table is or are applied to a porous support, and a second step in which the porous, preferably nanoporous support to which at least one precursor has been applied is treated with at least one reduction agent, to obtain the metal nanoparticles produced in situ in the pores of said support.

  本发明涉及一种在多孔载体颗粒上生产含有元素周期表 Ib 和 VIIIb 亚族金属组中的一种或几种金属的催化剂的方法，其特征在于第一步，将元素周期表 Ib 和 VIIIb 亚族金属化合物组中的一种或几种前体应用于多孔载体、第二步：用至少一种还原剂处理已使用至少一种前驱体的多孔（最好是纳米多孔）支撑物，以获得在所述支撑物孔隙中原位生成的金属纳米颗粒。
• [DE] VERFAHREN ZUR HERSTELLUNG VON PORÖS GETRÄGERTEN METALL-NANOPARTIKELHALTIGEN KATALYSATOREN, INSBESONDERE FÜR DIE GASPHASENOXIDATION VON ETHYLEN UND ESSIGSÄURE ZU VINYLACETAT<br/>[EN] METHOD FOR PRODUCING CATALYSTS CONTAINING METAL NANOPARTICLES ON A POROUS SUPPORT, ESPECIALLY FOR GAS PHASE OXIDATION OF ETHYLENE AND ACETIC ACID TO FORM VINYL ACETATE<br/>[FR] PROCEDE DE PRODUCTION DE CATALYSEURS CONTENANT DES NANOPARTICULES METALLIQUES A SUPPORT POREUX, EN PARTICULIER POUR L'OXYDATION EN PHASE GAZEUSE D'ETHYLENE ET D'ACIDE ACETIQUE EN ACETATE DE VINYLE
  申请人：CELANESE CHEMICALS EUROPE GMBH

  公开号：WO1999008791A1

  公开（公告）日：1999-02-25

  (DE) Ein erfindungsgemäßes Verfahren zur Herstellung eines auf porösen Trägerteilchen ein oder mehrere Metalle aus der Gruppe von Metallen, welche die Nebengruppen Ib und VIIIb des periodischen Systems der Elemente umfaßt, aufweisenden Katalysators, kennzeichnet sich dadurch, daß man in einem ersten Schritt einen porösen Träger mit einem oder mehreren Precursor(en) aus der Gruppe der Verbindungen, welche die Verbindungen der Metalle aus den Nebengruppen Ib und VIIIb des Periodensystems umfaßt, beaufschlagt; und daß man in einem zweiten Schritt den mit wenigstens einem Precursor beaufschlagten porösen, vorzugsweise nanoporösen, Träger mit wenigstens einem Reduktionsmittel unter Erhalt von in den Poren des Trägers in situ hergestellten metallenen Nanopartikeln behandelt.(EN) The invention relates to a method for producing a catalyst containing one or several metals from the group of metals comprising the sub-groups Ib and VIIIb of the periodic table on porous support particles, characterised by a first step in which one or several precursors from the group of compounds of metals from sub-groups Ib and VIIIb of the periodic table is or are applied to a porous support, and a second step in which the porous, preferably nanoporous support to which at least one precursor has been applied is treated with at least one reduction agent, to obtain the metal nanoparticles produced in situ in the pores of said support.(FR) L'invention concerne un procédé de production d'un catalyseur présentant un métal ou plusieurs métaux du groupe des métaux comprenant les sous-groupes Ib et VIIIb de la classification périodique des éléments, sur des particules de support poreuses. Ce procédé se caractérise en ce que: dans une première étape, on applique sur un support poreux un ou plusieurs précurseurs du groupe des composés comprenant les composés des métaux des sous-groupes Ib et VIIIb de la classification périodique des éléments; et, dans une seconde étape, on traite le support poreux, de préférence nanoporeux, sur lequel est appliqué au moins un précurseur, avec au moins un agent de réduction, ce qui permet d'obtenir des nanoparticules qui sont produites in situ dans les pores du support.

  一种通过孔径支撑颗粒制备带有至少一种金属的催化材料的方法，所述方法涉及两种工艺步骤。在第一工艺步骤中，一种或多种金属的前驱体，这些前驱体属于周期表中副族Ib和VIIIb的金属氧化物或有机前驱体，被施加到一种孔径支撑颗粒上；第二工艺步骤中，上述带有至少一个前驱体的孔径支撑颗粒（或其纳米孔径版本）被用一种或多种还原性试剂处理，以在支撑颗粒的大孔中形成金属纳米颗粒。