2-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide;(2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide;(2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
• 化学式: C38H51N7O6
• 分子量: 701.9
• InChiKey: JQKLLPZRXIPJRW-FTBISJDPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.61
• 重原子数：
  51
• 可旋转键数：
  18
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  197
• 氢给体数：
  5
• 氢受体数：
  10

文献信息

• DERMAL DELIVERY COMPOSITIONS COMPRISING ACTIVE AGENT-CALCIUM PHOSPHATE PARTICLE COMPLEXES AND METHODS OF USING THE SAME
  申请人：Laboratory Skin Care, Inc.

  公开号：EP2427178A2

  公开（公告）日：2012-03-14
• [EN] DERMAL DELIVERY COMPOSITIONS COMPRISING ACTIVE AGENT-CALCIUM PHOSPHATE PARTICLE COMPLEXES AND METHODS OF USING THE SAME<br/>[FR] COMPOSITIONS POUR LIBÉRATION DERMIQUE COMPRENANT DES COMPLEXES PRINCIPE ACTIF-PARTICULE DE PHOSPHATE DE CALCIUM ET PROCÉDÉS D'UTILISATION ASSOCIÉS
  申请人：LAB SKIN CARE INC

  公开号：WO2010129819A2

  公开（公告）日：2010-11-11

  Dermal delivery compositions are provided. Aspects of the dermal delivery compositions include the presence of active agent-calcium phosphate particle complexes, where these complexes include uniform, rigid, spherical nanoporous calcium phosphate particles associated with one or more active agents. Also provided are methods of using the compositions in active agent delivery applications.