3-[5-(1-Methoxyethyl)-3,6-dioxopiperazin-2-yl]propanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-[5-(1-Methoxyethyl)-3,6-dioxopiperazin-2-yl]propanoic acid
• 化学式: C₁₀H₁₆N₂O₅
• 分子量: 244.24
• InChiKey: NCQJVQUWULDHPF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  105
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• Composition for inhibiting hiv activity extracted from paecilomyces sp. (tochu-kaso) j300
  申请人：——

  公开号：US20040121963A1

  公开（公告）日：2004-06-24

  The present invention relates to a composition for inhibiting HIV activity comprising the extract of Paecilomyces sp. (Tochu-kaso) J300. More particularly, the present invention relates to a composition for inhibiting HIV activity comprising 3-[5-(methoxy-ethyl)-3,6-dioxo-piperazine-2-yl]propionic acid represented by Formula I and 4-methyl-2-[(pyrolidine-2-carbonyl)-2-amino] pentanoic acid represented by Formula 2 that are extracted from Paecilomyces sp. (Tochu-kaso) J300; and to a medical composition and food composition containing the same. 1

  本发明涉及一种抑制 HIV 活性的组合物，该组合物包含 Paecilomyces sp.（Tochu-kaso）J300 的提取物。更具体地说，本发明涉及一种抑制 HIV 活性的组合物，该组合物包含由式 I 代表的 3-[5-(甲氧基-乙基)-3,6-二氧代哌嗪-2-基]丙酸和由式 2 代表的 4-甲基-2-[(吡咯烷-2-羰基)-2-氨基]戊酸。(Tochu-kaso)J300中提取的；以及含有这些物质的医用组合物和食品组合物。 1
• COMPOSITION FOR INHIBITING HIV ACTIVITY EXTRACTED FROM i PAECILOMYCES SP. /i (TOCHU-KASO) J300
  申请人：Republic of Korea

  公开号：EP1389111A1

  公开（公告）日：2004-02-18
• US7704957B2
  申请人：——

  公开号：US7704957B2

  公开（公告）日：2010-04-27
• [EN] COMPOSITION FOR INHIBITING HIV ACTIVITY EXTRACTED FROM PAECILOMYCES SP. (TOCHU-KASO) J300<br/>[FR] COMPOSITION PERMETTANT D'INHIBER L'ACTIVITE DE VIH CONTENANT UN EXTRAIT DE PAECILOMYCES SP. (TOCHU-KASO) J300
  申请人：REPUBLIC KOREA

  公开号：WO2002080921A1

  公开（公告）日：2002-10-17

  The present invention relates to a composition form inhibiting HIV activity comprising the extract of Paecilomyces sp. (Tochu-kaso) J300. More particularly, the present invention relates to a composition for inhibiting HIV activity comprising 3-[5-(methoxy-ethyl)-3,6dioxo-piperazine-2-yl]propionic acid represented by Formula 1 and 4-methyl-2-[(pyrolidine-2-carbonyl)-2-amino] pentanoic acid represented by Formula 2 that are extracted from Paecilomyces sp. (Tochu-kaso) J300; and to a medical composition and food composition containing the same.