(S)-2-Amino-5-guanidinopentanoic acid 2-hydroxysuccinic acid (1:x) | 41989-03-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (S)-2-Amino-5-guanidinopentanoic acid 2-hydroxysuccinic acid (1:x)
• 英文别名: 2-amino-5-(diaminomethylideneamino)pentanoic acid;2-hydroxybutanedioic acid
• CAS: 41989-03-1
• 化学式: C10H20N4O7
• 分子量: 308.29
• InChiKey: RUFJTBOKWJYXPM-UHFFFAOYSA-N

物化性质

• 熔点：
  227-228℃ (decomposition)

计算性质

• 辛醇/水分配系数(LogP)：
  -2.64
• 重原子数：
  21
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  223
• 氢给体数：
  7
• 氢受体数：
  9

安全信息

• 海关编码：
  2925290090

文献信息

• Apo2 ligand/TRAIL formulations
  申请人：Genentech, Inc.

  公开号：EP2322165A1

  公开（公告）日：2011-05-18

  The inventions include Apo2L/TRAIL formulations and methods of using such formulations. Lyophilized and crystal formulations of Apo-2L/TRAIL which are stable and have improved Apo2L/TRAIL trimer formation are provided. Methods of making Apo-2L/TRAIL formulations, as well as devices and kits containing such formulations are also provided.

  本发明包括载脂蛋白 2L/TRAIL制剂和使用这种制剂的方法。本发明提供了稳定且具有更好的 Apo2L/TRAIL 三聚体形成的 Apo2L/TRAIL 冻干和晶体制剂。还提供了制造 Apo-2L/TRAIL 制剂的方法，以及含有此类制剂的设备和试剂盒。
• Electrophoresis apparatus and control method thereof
  申请人：ARKRAY, Inc.

  公开号：EP2418480A2

  公开（公告）日：2012-02-15

  An electrophoresis apparatus(1,80,140,150) that applies voltage from electrodes(21, 22,86,87) that are provided in a capillary flow channel(47,99) and causes component separation by performing electrophoresis on a specimen that is injected into the capillary flow channel(47,99) comprises: a physical quantity acquisition unit(71) and a physical quantity determination unit.The physical quantity acquisition unit (71), with migration solution and specimen injected inside the capillary flow channel (47, 99), acquires an electrical quantity that occurs in the capillary flow channel (47, 99) at a specified time when voltage is being applied to the electrodes (21, 22, 86, 87). The physical quantity determination unit (72) determines whether or not the electrical quantity that the physical acquisition unit (71) acquires is within a specified range.

  一种电泳仪(1,80,140,150)，可从设置在毛细管流动通道(47,99)中的电极(21,22,86,87)施加电压，并通过对注入毛细管流动通道(47,99)的试样进行电泳来实现成分分离，该电泳仪包括：物理量获取单元(71)和物理量确定单元。物理量采集单元（71）将迁移溶液和试样注入毛细管流道（47，99）内，当电压施加到电极（21，22，86，87）上时，采集指定时间内毛细管流道（47，99）内发生的电量。物理量确定单元（72）确定物理量获取单元（71）获取的电量是否在指定范围内。
• Chemical mechanical polishing method for tungsten
  申请人：Rohm and Haas Electronic Materials CMP Holdings, Inc.

  公开号：US10600655B2

  公开（公告）日：2020-03-24

  A process for chemical mechanical polishing a substrate containing tungsten to at least reduce dishing of tungsten features of 100 μm or less. The process includes providing a substrate containing tungsten features of 100 μm or less; providing a polishing composition, containing, as initial components: water; an oxidizing agent; arginine or salts thereof; a dicarboxylic acid, a source of iron ions; a colloidal silica abrasive; and, optionally, a pH adjusting agent; and, optionally, a surfactant; and, optionally, a biocide; providing a chemical mechanical polishing pad, having a polishing surface; creating dynamic contact at an interface between the polishing pad and the substrate; and dispensing the polishing composition onto the polishing surface at or near the interface between the polishing pad and the substrate; wherein some of the tungsten is polished away from the substrate and yet at least reducing dishing of the tungsten features of 100 μm or less.

  一种对含钨基底进行化学机械抛光以至少减少 100 μm 或以下钨特征的分层的工艺。该工艺包括提供含有 100 μm 或更小钨特征的基底；提供抛光组合物，作为初始成分，该组合物含有水；氧化剂；精氨酸或其盐；二羧酸；铁离子源；胶体二氧化硅磨料；可选的 pH 值调节剂；可选的表面活性剂；可选的杀菌剂；提供具有抛光表面的化学机械抛光垫；在抛光垫和基底之间的界面处产生动态接触；以及在抛光垫和基底之间的界面处或其附近将抛光组合物分配到抛光表面上；其中部分钨被抛光离开基底，但至少减少了 100 μm 或更小的钨特征的分层。
• Apo-2 ligand/trail formulations
  申请人：Flores Heather

  公开号：US20050020498A1

  公开（公告）日：2005-01-27

  The inventions include Apo2L/TRAIL formulations and methods of using such formulations. Lyophilized and crystal formulations of Apo-2L/TRAIL which are stable and have improved Apo2L/TRAIL trimer formation are provided. Methods of making Apo-2L/TRAIL formulations, as well as devices and kits containing such formulations are also provided.

  本发明包括载脂蛋白 2L/TRAIL制剂和使用这种制剂的方法。本发明提供了稳定且具有更好的 Apo2L/TRAIL 三聚体形成的 Apo2L/TRAIL 冻干和晶体制剂。还提供了制造 Apo-2L/TRAIL 制剂的方法，以及含有此类制剂的设备和试剂盒。
• Apo2 ligand/trail formulations
  申请人：Lin P. Tanya

  公开号：US20050080006A1

  公开（公告）日：2005-04-14

  The inventions include Apo2L/TRAIL formulations and methods of using such formulations. Lyophilized and crystal formulations of Apo-2L/TRAIL which are stable and have improved Apo2L/TRAIL trimer formation are provided. Methods of making Apo-2L/TRAIL formulations, as well as devices and kits containing such formulations are also provided.

  本发明包括载脂蛋白 2L/TRAIL制剂和使用这种制剂的方法。本发明提供了稳定且具有更好的 Apo2L/TRAIL 三聚体形成的 Apo2L/TRAIL 冻干和晶体制剂。还提供了制造 Apo-2L/TRAIL 制剂的方法，以及含有此类制剂的设备和试剂盒。