2-amino-6-(7-amino-3,4,5,6-tetrahydro-2H-azepin-2-yl)hexanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-amino-6-(7-amino-3,4,5,6-tetrahydro-2H-azepin-2-yl)hexanoic acid
• 化学式: C₁₂H₂₃N₃O₂
• 分子量: 241.33
• InChiKey: GFTXSVYMUGOAMJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.3
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  102
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• A SELECTIVE INOS INHIBITOR AND A PDE INHIBITOR IN COMBINATION FOR THE TREATMENT OF RESPIRATORY DISEASES
  申请人：Pharmacia Corporation

  公开号：EP1505972A2

  公开（公告）日：2005-02-16
• SELECTIVE INOS INHIBITORS FOR THE TREATMENT OF RESPIRATORY DISEASES AND CONDITIONS
  申请人：Pharmacia Corporation

  公开号：EP1506040A2

  公开（公告）日：2005-02-16
• [EN] METHODS FOR THE TREATMENT OF RESPIRATORY DISEASES AND CONDITIONS WITH A SELECTIVE INOS INHIBITOR AND A PDE INHIBITOR AND COMPOSITIONS THEREFOR<br/>[FR] METHODES DE TRAITEMENT DE MALADIES ET DE TROUBLES RESPIRATOIRES AVEC UN INHIBITEUR INOS SELECTIF ET UN INHIBITEUR PDE ET COMPOSITIONS A CET EFFET
  申请人：PHARMACIA CORP

  公开号：WO2003097050A2

  公开（公告）日：2003-11-27

  Therapeutic methods for the prevention and treatment of respiratory diseases or conditions are described, the methods including administering to a subject in need thereof a respiratory disease or condition effective amount of a selective inhibitor of inducible nitric oxide synthase.
• [EN] METHODS FOR THE TREATMENT OF RESPIRATORY DISEASES AND CONDITIONS USING A SELECTIVE INOS INHIBITOR<br/>[FR] METHODES DE TRAITEMENT DE MALADIES ET TROUBLES RESPIRATOIRES AU MOYEN D'UN INHIBITEUR SELECTIF DE L'INOS
  申请人：PHARMACIA CORP

  公开号：WO2003097163A2

  公开（公告）日：2003-11-27

  Therapeutic methods for the prevention and treatment of respiratory diseases or conditions are described, the methods including administering to a subject in need thereof a respiratory disease or condition effective amount of a selective inhibitor of inducible nitric oxide synthase.