Acrylic Acid Decylacrylate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Acrylic Acid Decylacrylate
• 英文别名: decyl prop-2-enoate;prop-2-enoic acid
• 化学式: C16H28O4
• 分子量: 284.39
• InChiKey: DCVHSBRCKUSAOA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.11
• 重原子数：
  20
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  丙烯酸 、 丙烯酸癸酯 在 偶氮二异丁腈 、 乙酸乙酯 作用下， 以 1,4-二氧六环 为溶剂， 反应 16.5h， 以to yield 9.0 g, 81% of a brittle white solid的产率得到Acrylic Acid Decylacrylate
  参考文献：
  名称：

  Anionic polymers as toxin binders and antibacterial agent

  摘要：

  本发明涉及一种通过向动物（如人类）施加具有多个直接附着于聚合物骨架或通过空间基团附着于聚合物骨架的垂饰酸官能团的聚合物的治疗有效量来抑制动物体内毒素的方法。空间基团的长度可以在0至约20个原子的范围内。毒素通常是由致病微生物（如细菌）分泌的外毒素。

  公开号：

  US06517827B1

文献信息

• Anionic polymers as toxin binders
  申请人：GelTex Pharmaceuticals, Inc.

  公开号：US20010041171A1

  公开（公告）日：2001-11-15

  The present invention relates to a method of inhibiting a toxin in an animal, such as a human, by administering to the animal a therapeutically effective amount of a polymer having a plurality of pendant acid functional groups which are directly attached to the polymer backbone or attached to the polymer backbone by a spacer group. The spacer group can have a length in the range from 0 to about 20 atoms. The toxin is, typically, an exotoxin secreted by a pathogenic microorganism, such as a bacterium.

  本发明涉及一种通过向动物（例如人类）施用具有多个挂链酸性官能团的聚合物的治疗有效量来抑制动物中毒素的方法。这些酸性官能团可以直接连接到聚合物骨架上，也可以通过一个间隔基团连接到聚合物骨架上。间隔基团的长度可以在0到约20个原子的范围内。毒素通常是由病原微生物（例如细菌）分泌的外毒素。
• Antiviral polymers comprising acid functional groups and hydrophobic groups
  申请人：GelTex Pharmaceuticals, Inc.

  公开号：US20020015946A1

  公开（公告）日：2002-02-07

  The present invention relates to a method of treating a viral infection in an animal, such as a human, by administering to the animal a therapeutically effective amount of a polymer comprising a plurality of pendant hydrophobic groups and a plurality of pendant acid functional groups. The acid functional groups are connected directly to the polymer backbone or via an aliphatic spacer group of 1 to about 20 atoms in length.

  本发明涉及一种治疗动物（例如人类）病毒感染的方法，通过向动物施用包含多个下垂疏水基团和多个下垂酸性功能基团的聚合物的治疗有效量。酸性功能基团直接连接到聚合物主链或通过长度为1到约20个原子的脂肪族间隔基团连接。
• Anionic polymers as toxin binders and antibacterial agent
  申请人：GelTex Pharmaceuticals, Inc.

  公开号：US06517827B1

  公开（公告）日：2003-02-11

  The present invention relates to a method of inhibiting a toxin in an animal, such as a human, by administering to the animal a therapeutically effective amount of a polymer having a plurality of pendant acid functional groups which are directly attached to the polymer backbone or attached to the polymer backbone by a spacer group. The spacer group can have a length in the range from 0 to about 20 atoms. The toxin is, typically, an exotoxin secreted by a pathogenic microorganism, such as a bacterium.

  本发明涉及一种通过向动物（如人类）施加具有多个直接附着于聚合物骨架或通过空间基团附着于聚合物骨架的垂饰酸官能团的聚合物的治疗有效量来抑制动物体内毒素的方法。空间基团的长度可以在0至约20个原子的范围内。毒素通常是由致病微生物（如细菌）分泌的外毒素。
• Anionic Polymers as Toxin Binders and Antibacterial Agents
  申请人：Bacon Kurtz Caroline Isabelle

  公开号：US20100172861A1

  公开（公告）日：2010-07-08

  The present invention relates to a method of inhibiting a toxin in an animal, such as a human, by administering to the animal a therapeutically effective amount of a polymer having a plurality of pendant acid functional groups which are directly attached to the polymer backbone or attached to the polymer backbone by a spacer group. The spacer group can have a length in the range from 0 to about 20 atoms. The toxin is, typically, an exotoxin secreted by a pathogenic microorganism, such as a bacterium.

  本发明涉及一种通过向动物，如人类，投放具有多个挂基酸功能团的聚合物的治疗有效量来抑制动物体内毒素的方法。这些挂基酸功能团直接连接到聚合物骨架上，或通过一个间隔基团连接到聚合物骨架上，该间隔基团的长度可在0至约20个原子范围内。该毒素通常是由致病微生物（如细菌）分泌的外毒素。
• LACTAMIC POLYMER CONTAINING AN ACETOACETATE MOIETY
  申请人：Hood David K.

  公开号：US20130261268A1

  公开（公告）日：2013-10-03

  The present invention provides lactamic polymers containing an acetoacetate moiety. The lactamic polymers may be readily functionalized and the functionalized lactamic polymers may be further derivatized to provide a wide variety of useful polymers having desirable chemical and physical properties. The lactamic polymers of the present invention may be employed in a wide variety of compositions. Formula (I) wherein R 1 -R 7 , x, y, z, and n are described herein.

  本发明提供了含有乙酰乙酸酯基团的内酰胺聚合物。这些内酰胺聚合物可以很容易地进行官能化，并且官能化的内酰胺聚合物可以进一步衍生化，以提供具有理想化学和物理性质的各种有用聚合物。本发明的内酰胺聚合物可以用于各种组合物中。式（I）中的R1-R7、x、y、z和n如本文所述。