This invention relates to the synthesis of certain complexes of cysteine, N-acetylcysteine, N-(2-mercaptopropionyl)glycine, and L-2-oxothiazolidine-4-carboxylate and to the nutritional use of these and other related individual or complexed thiol-contributing glutathione predecessors. Clinical uses for these molecules and complexes in the beneficial modification of various physiological conditions and functions associated with aging, chronic glaucoma, diabetes mellitus, insulin resistance, macular degeneration, neurodegenerative diseases and vasoconstriction are described in particular.
本发明涉及半胱
氨酸、N-乙酰半胱
氨酸、N-(2-巯基丙酰)甘
氨酸和
L-2-氧
噻唑啉-4-
羧酸的某些络合物的合成,以及这些和其他相关的单独或复合
硫醇贡献
谷胱甘肽前体的营养用途。特别地,描述了这些分子和复合物在有益地改变与衰老、慢性青光眼、糖尿病、
胰岛素抵抗、黄斑变性、神经退行性疾病和血管收缩等各种生理条件和功能相关的临床用途。