ethyl (2,3,4,5-tetraethylcyclopenta-2,4-dienylidene)acetate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: ethyl (2,3,4,5-tetraethylcyclopenta-2,4-dienylidene)acetate
• 英文别名: Ethyl 2-(2,3,4,5-tetraethylcyclopenta-2,4-dien-1-ylidene)acetate；ethyl 2-(2,3,4,5-tetraethylcyclopenta-2,4-dien-1-ylidene)acetate
• 化学式: C₁₇H₂₆O₂
• 分子量: 262.392
• InChiKey: XDGVQHMTQGKUTG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  19
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-己炔 、 ethyl (E)-3-iodopropenoate 在 palladium diacetate silver carbonate 作用下， 以 乙腈 为溶剂， 反应 3.0h， 以87%的产率得到ethyl (2,3,4,5-tetraethylcyclopenta-2,4-dienylidene)acetate
  参考文献：
  名称：

  Palladium-Catalyzed Coupling of Two Alkynes and an Alkenyl Iodide:  Formation of Pentasubstituted Fulvenes

  摘要：

  [GRAPHICS]Disubstituted alkynes reacted with alkenyl iodide in the presence of a catalytic amount of Pd(OAC)(2) and Ag2CO3 to give pentasubstituted fulvene derivatives in excellent yields. Other Ag salts such as AgNO3, AgBF4, and AgOTf are not effective, whereas a combination of AgNO3 and K2CO3 has a remarkable effect on the formation of fulvene.

  DOI：

  10.1021/ol016472f

文献信息

• Palladium-Catalyzed Coupling of Two Alkynes and an Alkenyl Iodide:  Formation of Pentasubstituted Fulvenes
  作者：Martin Kotora、Hiroshi Matsumura、Guohua Gao、Tamotsu Takahashi

  DOI：10.1021/ol016472f

  日期：2001.11.1

  [GRAPHICS]Disubstituted alkynes reacted with alkenyl iodide in the presence of a catalytic amount of Pd(OAC)(2) and Ag2CO3 to give pentasubstituted fulvene derivatives in excellent yields. Other Ag salts such as AgNO3, AgBF4, and AgOTf are not effective, whereas a combination of AgNO3 and K2CO3 has a remarkable effect on the formation of fulvene.