2-[2-(Pyrazine-2-carbonylamino)ethylamino]-3-sulfanylpropanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-[2-(Pyrazine-2-carbonylamino)ethylamino]-3-sulfanylpropanoic acid
• 化学式: C₁₀H₁₄N₄O₃S
• 分子量: 270.31
• InChiKey: WISOVVJYHCGJDB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.4
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  105
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• IMAGING TUBERCULOSIS WITH PYRAZINAMIDE CONTRAST AGENTS
  申请人：Kuniyil Kulangara Vijaya Raj

  公开号：US20130149249A1

  公开（公告）日：2013-06-13

  The present invention provides novel in vivo imaging agents useful for detecting the presence of mycobacteria using in vivo imaging methods. Also provided by the present invention is a precursor compound useful in the synthesis of the in vivo imaging agents of the invention, and a method to obtain the in vivo imaging agent of the invention using said precursor compound. Methods of in vivo imaging and diagnosis in which the in vivo imaging agent of the invention finds use are also provided.

  本发明提供了一种新型的体内成像剂，可用于使用体内成像方法检测结核分枝杆菌的存在。本发明还提供了一种前体化合物，用于合成本发明的体内成像剂，以及使用该前体化合物获得本发明的体内成像剂的方法。本发明还提供了使用本发明的体内成像剂进行体内成像和诊断的方法。
• [EN] IMAGING TUBERCULOSIS WITH PYRAZINAMIDE CONTRAST AGENTS<br/>[FR] IMAGERIE DE LA TUBERCULOSE AU MOYEN D'AGENTS DE CONTRASTE DE TYPE PYRAZINAMIDE
  申请人：GE HEALTHCARE LTD

  公开号：WO2012022812A1

  公开（公告）日：2012-02-23

  The present invention provides novel in vivo imaging agents useful for detecting the presence of mycobacteria using in vivo imaging methods. Also provided by the present invention is a precursor compound useful in the synthesis of the in vivo imaging agents of the invention, and a method to obtain the in vivo imaging agent of the invention using said precursor compound. Methods of in vivo imaging and diagnosis in which the in vivo imaging agent of the invention finds use are also provided.