N-(cyanomethyl)-2-(cyclohexylmethyl)-N'-methyl-N'-propylpropanediamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N-(cyanomethyl)-2-(cyclohexylmethyl)-N'-methyl-N'-propylpropanediamide
• 化学式: C₁₆H₂₇N₃O₂
• 分子量: 293.4
• InChiKey: VWRMMRMYSXENKF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  21
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  73.2
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Novel compounds and compositions as cathepsin inhibitors
  申请人：——

  公开号：US20040147503A1

  公开（公告）日：2004-07-29

  The present invention relates to novel selective cathepsin S inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.

  本发明涉及新型选择性卡特普西林S抑制剂，其药学上可接受的盐和N-氧化物，其作为治疗剂的用途以及其制备方法。
• Novel Compounds and Compositions as Cathepsin Inhibitors
  申请人：Patterson W. John

  公开号：US20070232654A1

  公开（公告）日：2007-10-04

  The present invention relates to novel selective cathepsin S inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.

  本发明涉及新型选择性卡特普西林S抑制剂，其药学上可接受的盐和N-氧化物，以及它们作为治疗剂的用途和制备方法。
• NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS
  申请人：AXYS PHARMACEUTICALS, INC.

  公开号：EP1399146A1

  公开（公告）日：2004-03-24
• EP1399146A4
  申请人：——

  公开号：EP1399146A4

  公开（公告）日：2006-01-18
• [EN] NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS<br/>[FR] COMPOSES ET COMPOSITIONS D'INHIBITEURS DE CATHEPSINE
  申请人：CELERA

  公开号：WO2002098406A1

  公开（公告）日：2002-12-12

  The present invention relates to novel selective cathepsin S inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making,