2-Amino-N-(3,4-dichloro-phenyl)-2-[(Z)-hydroxyimino]-acetamide | 220898-97-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-Amino-N-(3,4-dichloro-phenyl)-2-[(Z)-hydroxyimino]-acetamide
• 英文别名: (2Z)-2-amino-N-(3,4-dichlorophenyl)-2-hydroxyiminoacetamide
• CAS: 220898-97-5
• 化学式: C₈H₇Cl₂N₃O₂
• 分子量: 248.068
• InChiKey: WEHANJUKFPDDLA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  87.7
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-Amino-N-(3,4-dichloro-phenyl)-2-[(Z)-hydroxyimino]-acetamide 在 硫酸 、 sodium nitrite 作用下， 以 水 为溶剂， 反应 0.25h， 以82%的产率得到3,4-bis[N-(3,4-dichlorophenyl)carbamoyl]furoxane
  参考文献：
  名称：

  摘要：

  Carbamoylformhydroxymoyl chlorides were synthesized by the reactions of carbamoylformamide oximes with sodium nitrine, in the presence of hydrochloric acid, and their reactivities were examined.

  DOI：

  10.1023/a:1020971225125
• 作为产物：
  描述：

  N-(3,4-Dichlorophenyl)-2-morpholin-4-yl-2-thioxoacetamide 在 盐酸羟胺 作用下， 以 吡啶 为溶剂， 反应 0.75h， 以96%的产率得到2-Amino-N-(3,4-dichloro-phenyl)-2-[(Z)-hydroxyimino]-acetamide
  参考文献：
  名称：

  Synthesis of carbamoylamidoximes

  摘要：

  A convenient procedure was developed for the synthesis of carbamoylamidoximes by the reaction of N(S)-substituted monothiooxamides with hydroxylamine hydrochloride in pyridine.

  DOI：

  10.1007/bf02494503

文献信息

• ——
  作者：V. N. Yarovenko、S. A. Kosarev、I. V. Zavarzin、M. M. Krayushkin

  DOI：10.1023/a:1021348401329

  日期：——

  A convenient method for the synthesis of 3-carbamoyl-1,2,4-oxadiazoles from carbamoyl-amidoximes and chlorides or anhydrides of haloacetic acids was developed. The reactions of 3-carbamoyl-5-trichloromethyl-1,2,4-oxadiazoles with amines and N,N-dimethylhydrazine were studied.
• ——
  作者：V. N. Yarovenko、S. A. Kosarev、I. V. Zavarzin、M. M. Krayushkin

  DOI：10.1023/a:1020971225125

  日期：——

  Carbamoylformhydroxymoyl chlorides were synthesized by the reactions of carbamoylformamide oximes with sodium nitrine, in the presence of hydrochloric acid, and their reactivities were examined.
• Synthesis of carbamoylamidoximes
  作者：V. N. Yarovenko、S. A. Kosarev、I. V. Zavarzin、M. M. Krayushkin

  DOI：10.1007/bf02494503

  日期：1998.10

  A convenient procedure was developed for the synthesis of carbamoylamidoximes by the reaction of N(S)-substituted monothiooxamides with hydroxylamine hydrochloride in pyridine.