(+/-)-2-((6S)-6-(aminomethyl)bicyclo[3.2.0]heptan-6-yl)acetic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (+/-)-2-((6S)-6-(aminomethyl)bicyclo[3.2.0]heptan-6-yl)acetic acid
• 英文别名: 2-[(6S)-6-(aminomethyl)-6-bicyclo[3.2.0]heptanyl]acetic acid
• 化学式: C₁₀H₁₇NO₂
• 分子量: 183.25
• InChiKey: JXSBZOVCVUSLIO-SFVIPPHHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.3
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  63.3
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• A PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF ADDICTION IN A MAMMAL
  申请人：Pfizer Products Inc.

  公开号：EP1658058A1

  公开（公告）日：2006-05-24
• [EN] A PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF ADDICTION IN A MAMMAL<br/>[FR] COMPOSITION PHARMACEUTIQUE POUR LA PREVENTION ET LE TRAITEMENT DE L'ACCOUTUMANCE CHEZ UN MAMMIFERE
  申请人：PFIZER PROD INC

  公开号：WO2005018621A1

  公开（公告）日：2005-03-03

  Pharmaceutical compositions are disclosed for the treatment of alcohol or cocaine dependence or addiction, alcohol dependence or addiction, reduction of alcohol withdrawal symptoms or aiding in the cessation or lessening of tobacco use or substance abuse or other behavioral dependencies. The pharmaceutical compositions are comprised of a therapeutically effective combination of a nicotinic receptor partial agonist and an alpha2delta ligand and a pharmaceutically acceptable carrier. The method of using these compounds is also disclosed.