(1S,2S,4S,6R,7S)-N-(2-amino-2-oxoethyl)-2,4-dimethylbicyclo[4.1.0]heptane-7-carboxamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (1S,2S,4S,6R,7S)-N-(2-amino-2-oxoethyl)-2,4-dimethylbicyclo[4.1.0]heptane-7-carboxamide
• 化学式: C₁₂H₂₀N₂O₂
• 分子量: 224.303
• InChiKey: ZMHUKJSJVCQBEU-YBSMEWOOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  72.2
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Fused cycloalkyl amides and acids and their therapeutic applications
  申请人：——

  公开号：US20040209859A1

  公开（公告）日：2004-10-21

  The present invention relates to the use of compounds of formula (I) 1 for the treatment of epilepsy, bipolar disorder, psychiatric disorders, migraine, pain, or movement disorders, and to provide neuroprotection.

  本发明涉及使用式(I)1化合物治疗癫痫、双相情感障碍、精神障碍、偏头痛、疼痛或运动障碍，并提供神经保护。
• FUSED CYCLOALKYL AMIDES AND ACIDS AND THEIR THERAPEUTIC APPLICATIONS FOR THE TREATMENT OF I.A. EPILEPSY
  申请人：Abbott Laboratories

  公开号：EP1562575A1

  公开（公告）日：2005-08-17
• [EN] FUSED CYCLOALKYL AMIDES AND ACIDS AND THEIR THERAPEUTIC APPLICATIONS FOR THE TREATMENT OF I.A. EPILEPSY<br/>[FR] CYCLOALKYLAMIDES ET ACIDES CONDENSES ET LEURS APPLICATIONS THERAPEUTIQUES NOTAMMENT DANS LE TRAITEMENT DE L'EPILEPSIE
  申请人：ABBOTT LAB

  公开号：WO2004037241A1

  公开（公告）日：2004-05-06

  The present invention relates to the use of compounds of formula (I) for the treatment of epilepsy, bipolar disorder, psychiatric disorders, migraine, pain, or movement disorders, and to provide neuroprotection.