1,4-anhydroerythritol 1,4-anhydro-D-threitol 2(SR):2'(RS) anhydride

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧唑烯
• 英文名称: 1,4-anhydroerythritol 1,4-anhydro-D-threitol 2(SR):2'(RS) anhydride
• 英文别名: (3R,4S)-4-[(3R,4R)-4-hydroxyoxolan-3-yl]oxyoxolan-3-ol
• 化学式: C₈H₁₄O₅
• 分子量: 190.196
• InChiKey: ZPVIGJUORCVDPM-XUTVFYLZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.8
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  68.2
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  Erythritol 在 3 A molecular sieve 、 zeolite LTA (SiO₂:Al₂O₃=1:1) 作用下， 反应 4.0h， 生成 anhydroerythritol 、 trans-tetrahydrofuran-3,4-diol 、 bis(1,4-anhydroerythritol) 2(RS),2'(SR) anhydride 、 1,4-anhydroerythritol 1,4-anhydro-D-threitol 2(SR):2'(RS) anhydride
  参考文献：
  名称：

  The solvent-free thermal dehydration of tetritols on zeolites

  摘要：

  A new alditol dehydration method at high temperatures, in the presence of molecular sieves without solvent in an argon atmosphere, is described. Investigations on tetritols have been carried out. Products arising after the intramolecular and intermolecular elimination of water, with retention or inversion of the configuration of asymmetric carbon atoms, were observed. Complete analytical separation of reaction products was achieved by means of GLC. The chemical structures of the compounds obtained were assigned using co-injection with standards, GLC-CIMS and GLC-EIMS analyses. Two intermolecular dehydration products of tetritols were isolated by HPLC and identified by H-1 and C-13 NMR spectroscopy. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0008-6215(00)00047-1

文献信息

• The solvent-free thermal dehydration of tetritols on zeolites
  作者：Maria Kurszewska、Eugenia Skorupa、Regina Kasprzykowska、Paweł Sowiński、Andrzej Wiśniewski

  DOI：10.1016/s0008-6215(00)00047-1

  日期：2000.6

  A new alditol dehydration method at high temperatures, in the presence of molecular sieves without solvent in an argon atmosphere, is described. Investigations on tetritols have been carried out. Products arising after the intramolecular and intermolecular elimination of water, with retention or inversion of the configuration of asymmetric carbon atoms, were observed. Complete analytical separation of reaction products was achieved by means of GLC. The chemical structures of the compounds obtained were assigned using co-injection with standards, GLC-CIMS and GLC-EIMS analyses. Two intermolecular dehydration products of tetritols were isolated by HPLC and identified by H-1 and C-13 NMR spectroscopy. (C) 2000 Elsevier Science Ltd. All rights reserved.