1,3-bis(4-methoxyphenyl)anthracene-9,10-dione

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,3-bis(4-methoxyphenyl)anthracene-9,10-dione
• 英文别名: 1,3-bis(4-methoxyphenyl)-9,10-anthraquinone
• 化学式: C₂₈H₂₀O₄
• 分子量: 420.464
• InChiKey: FFFGACDMGTYXTB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  32
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  δ-Hydroxy-β,δ-bis(p-methoxyphenyl)-α,γ-pentadienoic acid δ-lactone 在 tetraphosphorus decasulfide 、 sodium carbonate 作用下， 以 1,4-二氧六环 、 甲醇 、 水 、 硝基苯 为溶剂， 反应 16.5h， 生成 1,3-bis(4-methoxyphenyl)anthracene-9,10-dione
  参考文献：
  名称：

  Pai, Ruchira R.; Bendre, Deven S.; Samant, Shriniwas D., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002, vol. 41, # 1, p. 191 - 195

  摘要：

  DOI：

文献信息

• Synthesis of arylated anthraquinones by site-selective Suzuki–Miyaura reactions of the bis(triflates) of 1,3-di(hydroxy)anthraquinones
  作者：Omer A. Akrawi、Afsar Khan、Tamás Patonay、Alexander Villinger、Peter Langer

  DOI：10.1016/j.tet.2013.08.041

  日期：2013.10

  were prepared by Suzuki–Miyaura reactions of the bis(triflates) of various 1,3-(dihydroxy)anthraquinones. While the reactions of the bis(triflates) of parent 1,3-(dihydroxy)anthraquinone and of 2-chloro-1,3-di(hydroxy)anthraquinone proceeded with very good site-selectivity, the corresponding reactions of the bis(triflate) of 2-fluoro-1,3-diarylanthraquinones were not site-selective, which was explained

  芳基化的蒽醌类是由不同的1,3-（二羟基）蒽醌的双（三氟甲磺酸酯）的铃木 - 宫浦反应制备。虽然双父（三氟甲磺酸酯）1,3-（二羟基）蒽醌-2-氯-1,3-二的和的反应（羟基）蒽醌进行具有非常好的位点的选择性，所述之二的相应的反应（三氟甲磺酸酯）2-氟-1,3-二芳基蒽醌不是位点选择性的，这是基于氟原子的π供电作用来解释的。
• Site-selective Suzuki-Miyaura reactions of the bis(triflate) of 1,3-dihydroxyanthraquinone
  作者：Omer A. Akrawi、Munawar Hussain、Peter Langer

  DOI：10.1016/j.tetlet.2010.12.098

  日期：2011.3

  Various aryl-substituted anthraquinones were prepared by palladium(0)-catalyzed Suzuki-Miyaura cross-coupling reactions of the bis(triflate) of 1,3-dihydroxyanthraquinone. A very good site-selectivity ill favor of position 1 was observed which can be explained by the electronic influence of the neighboring carbonyl group. (C) 2011 Published by Elsevier Ltd.
• Kamath, Chitra R.; Samant, Shriniwas D., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1996, vol. 35, # 3, p. 256 - 259
  作者：Kamath, Chitra R.、Samant, Shriniwas D.

  DOI：——

  日期：——
• Kamath, Chitra R.; Samant, Shriniwas D., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999, vol. 38, # 10, p. 1214 - 1217
  作者：Kamath, Chitra R.、Samant, Shriniwas D.

  DOI：——

  日期：——
• Prabhu; Samant, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1996, vol. 35, # 1, p. 14 - 18
  作者：Prabhu、Samant

  DOI：——

  日期：——