[2-hydroxy-3,5-bis(1-phenylethyl)phenyl]methylaminodiacetic acid

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: [2-hydroxy-3,5-bis(1-phenylethyl)phenyl]methylaminodiacetic acid
• 英文别名: 2-[Carboxymethyl-[[2-hydroxy-3,5-bis(1-phenylethyl)phenyl]methyl]amino]acetic acid；2-[carboxymethyl-[[2-hydroxy-3,5-bis(1-phenylethyl)phenyl]methyl]amino]acetic acid
• 化学式: C₂₇H₂₉NO₅
• 分子量: 447.531
• InChiKey: URALWXOLNCWTKV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  33
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  98.1
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  聚合甲醛 、 2,4-双-(1-苯基乙基)苯酚 、 亚氨基二乙酸 在 sodium hydroxide 作用下， 反应 3.0h， 以66%的产率得到[2-hydroxy-3,5-bis(1-phenylethyl)phenyl]methylaminodiacetic acid
  参考文献：
  名称：

  Synthesis and studies of some metal-containing derivatives of [2-Hydroxy-3,5-di-(1-phenylethyl)phenyl]methylaminodiacetic acid

  摘要：

  [2-Hydroxy- 3,5-di-(1-phenylethyl) phenyl]methylaminodiacetic acid and its complexes with transition metals, Cu(II), Co(II), and Ni(II), were synthesized and studied. Protonated (MeHL) and deprotonated (MeL) complexes were prepared. It was found that of copper(II), cobalt(II), and nickel(II), [2-hydroxy-3,5-di-(1-phenylethyl)phenyl]methylaminodiacetates are effective as antiwear and antiscore agents.

  DOI：

  10.1134/s0965544107020065

文献信息

• Synthesis and studies of some metal-containing derivatives of [2-Hydroxy-3,5-di-(1-phenylethyl)phenyl]methylaminodiacetic acid
  作者：P. Sh. Mamedova、V. M. Farzaliev、E. R. Babaev、S. A. Gamzaeva

  DOI：10.1134/s0965544107020065

  日期：2007.3

  [2-Hydroxy- 3,5-di-(1-phenylethyl) phenyl]methylaminodiacetic acid and its complexes with transition metals, Cu(II), Co(II), and Ni(II), were synthesized and studied. Protonated (MeHL) and deprotonated (MeL) complexes were prepared. It was found that of copper(II), cobalt(II), and nickel(II), [2-hydroxy-3,5-di-(1-phenylethyl)phenyl]methylaminodiacetates are effective as antiwear and antiscore agents.