(2S)-3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]-2-hydroxypropane-1-sulfonic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: (2S)-3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]-2-hydroxypropane-1-sulfonic acid
• 化学式: C₇H₁₇NO₇S
• 分子量: 259.28
• InChiKey: RZQXOGQSPBYUKH-LURJTMIESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -6.4
• 重原子数：
  16
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  156
• 氢给体数：
  6
• 氢受体数：
  8

文献信息

• [EN] RNA PARTICLES COMPRISING POLYSARCOSINE<br/>[FR] PARTICULES D'ARN COMPRENANT DE LA POLYSARCOSINE
  申请人：BIONTECH RNA PHARMACEUTICALS GMBH

  公开号：WO2021191265A1

  公开（公告）日：2021-09-30

  The present disclosure relates to RNA particles for delivery of RNA to target tissues after administration, in particular after parenteral administration such as intravenous, intramuscular, subcutaneous or intratumoral administration, and compositions comprising such RNA particles. The RNA particles in one embodiment comprise single-stranded RNA such as mRNA which encodes a peptide or protein of interest, such as a pharmaceutically active peptide or protein. The RNA is taken up by cells of a target tissue and the RNA is translated into the encoded peptide or protein, which may exhibit its physiological activity.