吡啶正离子,2-[4-[4-(二甲氨基)苯基]-1,3-丁二烯基]-1-甲基-,碘化 | 139557-65-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 吡啶正离子,2-[4-[4-(二甲氨基)苯基]-1,3-丁二烯基]-1-甲基-,碘化
• 英文名称: 2-<4-(4-dimethylaminophenyl)-1,3-butadienyl>-1-methylpyridinium iodide
• 英文别名: 2-[4-(4-dimethylaminophenyl)-1,3-butadienyl]-1-methylpyridinium iodide；2-(4-(4-(Dimethylamino)phenyl)-1,3-butadienyl)-1-methylpyridinium iodide；N,N-dimethyl-4-[4-(1-methylpyridin-1-ium-2-yl)buta-1,3-dienyl]aniline;iodide
• CAS: 139557-65-6
• 化学式: C₁₈H₂₁N₂*I
• 分子量: 392.283
• InChiKey: ANUHDHVUOVBKMV-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.31
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  7.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  碘化1,2-二甲基吡啶鎓 在 四氢吡咯 作用下， 以 乙醇 、 乙二醇 为溶剂， 反应 0.05h， 生成 吡啶正离子,2-[4-[4-(二甲氨基)苯基]-1,3-丁二烯基]-1-甲基-,碘化
  参考文献：
  名称：

  Combinatorial Approach to Organelle-Targeted Fluorescent Library Based on the Styryl Scaffold

  摘要：

  The first fluorescent styryl dye library with a broad color range was synthesized by combinatorial condensation of various aldehydes and methyl pyridinium compounds, and their applications as organelle specific staining probes were demonstrated.

  DOI：

  10.1021/ja027587x

文献信息

• Synthesis and Characterization of Mono-, Bis-, and Trissubstituted Pyridinium and Pyrylium Dyes
  作者：Masaki Matsui、Shigeo Kawamura、Katsuyoshi Shibata、Hiroshige Muramatsu

  DOI：10.1246/bcsj.65.71

  日期：1992.1

  A series of mono-, bis-, and trissubstituted pyridinium and pyrylium dyes have been synthesized by the condensation of methylpyridinium and methylpyrylium salts with aldehydes or nitroso compound. Large bathochromic shifts were observed in the following order, both in substituted azomethine pyridinium and pyrylium dyes, mono < bis < tris. The magnitude of the shift appeared in the order of multiple

  通过甲基吡啶鎓和甲基吡啶鎓盐与醛或亚硝基化合物缩合合成了一系列单、双和三取代的吡啶鎓和吡咯鎓染料。在取代的偶氮甲碱吡啶鎓和吡咯鎓染料中，按以下顺序观察到大的红移，单<双<三。位移的大小以多重键的顺序出现，–CH=CH– < –CH=CH–CH=CH– < –CH=N–。
• Combinatorial Approach to Organelle-Targeted Fluorescent Library Based on the Styryl Scaffold
  作者：Gustavo R. Rosania、Jae Wook Lee、Liang Ding、Hai-Shin Yoon、Young-Tae Chang

  DOI：10.1021/ja027587x

  日期：2003.2.1

  The first fluorescent styryl dye library with a broad color range was synthesized by combinatorial condensation of various aldehydes and methyl pyridinium compounds, and their applications as organelle specific staining probes were demonstrated.