tert-butyl-[(1S)-3-oxocyclohexyl]carbamic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: tert-butyl-[(1S)-3-oxocyclohexyl]carbamic acid
• 化学式: C₁₁H₁₉NO₃
• 分子量: 213.27
• InChiKey: IQLWWXRHIIEPSX-QMMMGPOBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  57.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• AZAINDOLE DERIVATIVE
  申请人：TAIHO PHARMACEUTICAL CO., LTD.

  公开号：US20160340353A1

  公开（公告）日：2016-11-24

  Provided is a novel compound having a selective JAK3-inhibitory effect and also having excellent oral absorbability. Also provided is a pharmaceutical agent, which is based on a JAK3-inhibitory effect and is useful for preventing and/or treating a disease involving the JAK3, and in particular, rheumatoid arthritis or multiple sclerosis. An azaindole derivative having a cycloalkenyl group, which is represented by the following formula (I), or a salt thereof, and a pharmaceutical composition containing the same: where R 1 to R 4 , m and n have the same meanings as those defined in the description.
• US9676773B2
  申请人：——

  公开号：US9676773B2

  公开（公告）日：2017-06-13