(E)-1-(1-heptenyl)-3-methylbenzene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-1-(1-heptenyl)-3-methylbenzene
• 英文别名: 1-[(E)-hept-1-enyl]-3-methylbenzene
• 化学式: C₁₄H₂₀
• 分子量: 188.313
• InChiKey: SYUTYKOUIPGJPC-JXMROGBWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  1-庚炔 、 间碘甲苯 在 t-Bu₃P-Pt(1,3-divinyl-1,1,3,3-tetramethyldisiloxane) 、 bis(dibenzylideneacetone)-palladium⁽⁰⁾ 1,1,3,3-四甲基二硅氧烷 、 四丁基氟化铵 作用下， 以 四氢呋喃 为溶剂， 反应 0.67h， 生成 、 (E)-1-(1-heptenyl)-3-methylbenzene 、 1-Methyl-3-(1-methylene-hexyl)-benzene
  参考文献：
  名称：

  Highly Stereoselective Hydrocarbation of Terminal Alkynes via Pt-Catalyzed Hydrosilylation/Pd-Catalyzed Cross-Coupling Reactions

  摘要：

  [GRAPHICS]The formal addition of an aryl-H or alkenyl-H bond across a terminal alkyne has been accomplished by the combination of platinum-catalyzed hydrosilylation followed by palladium-catalyzed cross-coupling, The use of the t-Bu3P-Pt(DVDS) catalyst in combination with tetramethyldisiloxane gave excellent regio- and stereoselectivity with a number of alkyne substrates, Subsequent, fluoride-promoted cross-coupling proceeded in high yield and stereospecificity for a variety of aryl halides.

  DOI：

  10.1021/ol0156751

文献信息

• Highly Stereoselective Hydrocarbation of Terminal Alkynes via Pt-Catalyzed Hydrosilylation/Pd-Catalyzed Cross-Coupling Reactions
  作者：Scott E. Denmark、Zhigang Wang

  DOI：10.1021/ol0156751

  日期：2001.4.1

  [GRAPHICS]The formal addition of an aryl-H or alkenyl-H bond across a terminal alkyne has been accomplished by the combination of platinum-catalyzed hydrosilylation followed by palladium-catalyzed cross-coupling, The use of the t-Bu3P-Pt(DVDS) catalyst in combination with tetramethyldisiloxane gave excellent regio- and stereoselectivity with a number of alkyne substrates, Subsequent, fluoride-promoted cross-coupling proceeded in high yield and stereospecificity for a variety of aryl halides.