(ethynyl)(sulfanyl)benzene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯硫酚类
• 英文名称: (ethynyl)(sulfanyl)benzene
• 英文别名: (ethynylphenyl) thiol；2-ethynylbenzenethiol；o-Ethynyl-thiophenol
• 化学式: C₈H₆S
• 分子量: 134.202
• InChiKey: DYNBNOLIHUTXSO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (ethynyl)(sulfanyl)benzene 在 oxone 、 sodium iodide 作用下， 以 四氢呋喃 为溶剂， 反应 24.0h， 以92%的产率得到3-碘苯并[b]噻吩
  参考文献：
  名称：

  Oxone®-mediated halocyclization/demethylation of 2-alkynylthioanisoles with sodium halides towards 3-halobenzo[b]thiophenes

  摘要：

  DOI：

  10.1016/j.tetlet.2021.153614

文献信息

• ACETYLENE COMPOUND
  申请人：Fujifilm Corporation

  公开号：EP2202221A1

  公开（公告）日：2010-06-30

  The invention provides an acetylene compound represented by the following Formula (1), which is useful as a raw material for a polymer achieving high thermal resistance; wherein, in Formula (1), the encircled Ar represents an aryl group or a heteroaryl group; X represents a divalent linking group; R, R' and R1 each independently represent a hydrogen atom, a hydrocarbon group or a heterocyclic group; R2 represents a hydrogen atom or a substituent substitutable on a benzene ring; A represents a hydrocarbon group or a heterocyclic group; Q represents a hydrogen atom, a hydrocarbon group, or a metal element capable of forming a monovalent metal salt; a represents an integer from 0 or more; b, m and n each independently represent an integer of 1 or more; when n, m and b are 1 at the same time, X is not -(C=O)O-; and when n is 2, and both m and b are 1, X is not -O-.

  本发明提供了一种由下式（1）表示的乙炔化合物，它可用作具有高耐热性的聚合物的原料； 其中，在式(1)中，环绕的 Ar 代表芳基或杂芳基；X 代表二价连接基团；R、R'和 R1 各自独立地代表氢原子、烃基或杂环基团；R2 代表氢原子或可取代苯环的取代基；A 代表烃基或杂环基团；Q代表氢原子、烃基或能形成一价金属盐的金属元素；a代表0或0以上的整数；b、m和n各自独立地代表1或1以上的整数；当n、m和b同时为1时，X不是-(C=O)O-；当n为2且m和b均为1时，X不是-O-。
• Diagnostics, drug screening and treatment for cancer
  申请人：Minerva Biotechnologies Corporation

  公开号：EP2241887A2

  公开（公告）日：2010-10-20

  The invention provides a series of compositions, methods, kits, articles and species associated primarily with the diagnosis and/or treatment of cell proliferation, specifically cancer. Cell proliferation associated with aberrant expression of MUCI is particularly focused upon. Mechanisms associated with MUCI cell proliferation are discussed.

  本发明提供了一系列主要与诊断和/或治疗细胞增殖（特别是癌症）有关的组合物、方法、试剂盒、物品和物种。与 MUCI 异常表达相关的细胞增殖尤其受到关注。讨论了与 MUCI 细胞增殖相关的机制。
• Assays involving sam-modified colloids and non-colloidal structures
  申请人：Minerva Biotechnologies Corporation

  公开号：EP2320231A2

  公开（公告）日：2011-05-11

  The invention provides novel techniques for derivatizing colloids with self-assembled monolayers. This provides the capability of a wide variety of assays including chemical or biochemical agent/agent interaction studies. Bio-derivatized colloids, with or without signaling entities, are used to probe interactions with species on non-colloidal structures. The invention provides techniques for immobilizing colloidal particles on a wide variety of non-colloidal structures. Included is the ability to decorate a variety of non-colloidal structures including beads, with colloids as a detectable assay. This allows, in many cases, assays detectable via the unaided human eye, as well as assays detectable via automated determination of a change of interaction of electromagnetic radiation with the colloids, e.g., absorption, light-scattering, and the like.

  本发明提供了用自组装单层衍生胶体的新技术。这提供了多种检测能力，包括化学或生化制剂/制剂相互作用研究。含有或不含信号实体的生物衍生胶体可用于探测与非胶体结构上物种的相互作用。本发明提供了将胶体颗粒固定在各种非胶体结构上的技术。其中包括用胶体装饰包括珠子在内的各种非胶体结构，作为一种可检测的化验方法。这样，在许多情况下，既可以通过辅助人眼进行检测，也可以通过自动测定电磁辐射与胶体相互作用的变化（如吸收、光散射等）进行检测。
• Oligonucleotide identifiers
  申请人：Minerva Biotechnologies Corporation

  公开号：EP2360275A1

  公开（公告）日：2011-08-24

  Methods, assays, and components are described in which biological samples can be rapidly and sensitively analyzed for the presence of species associated with neurodegenerative disease. Techniques and components are provided for diagnosis of disease, as well as for screening of candidate drugs for treatment of neurodegenerative disease. The techniques are simple, extremely sensitive, and utilize readily-available components. Binding species, capable of binding a neurodegenerative disease aggregate-forming or aggregate-forming species, are fastened to surfaces of electrodes and surfaces of particles, or provided free in solution, to bind aggregate-forming species and/or be involved in aggregation.

  本文描述了可以快速灵敏地分析生物样本中是否存在与神经退行性疾病相关的物种的方法、检测方法和组件。提供的技术和组件可用于疾病诊断以及治疗神经退行性疾病的候选药物筛选。这些技术简单易行、灵敏度极高，并采用了现成的元件。能够结合神经退行性疾病聚合体形成物或聚合体形成物的结合物被固定在电极表面和颗粒表面，或在溶液中自由提供，以结合聚合体形成物和/或参与聚合。
• Isoforms of MUC1
  申请人：Minerva Biotechnologies Corporation

  公开号：EP2363410A1

  公开（公告）日：2011-09-07

  The invention provides a series of compositions, methods, kits, articles and species associated primarily with the diagnosis and/or treatment of cell proliferation, specifically cancer. Cell proliferation associated with aberrant expression of MUC1 is particularly focused upon. Mechanisms associated with MUCl cell proliferation are discussed.

  本发明提供了一系列主要与诊断和/或治疗细胞增殖（特别是癌症）有关的组合物、方法、试剂盒、物品和物种。与 MUC1 异常表达相关的细胞增殖尤其受到关注。讨论了与 MUCl 细胞增殖相关的机制。