N-(2,4,6-trimethyl-3-cyanophenyl)-2,4,6-trimethylbenzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(2,4,6-trimethyl-3-cyanophenyl)-2,4,6-trimethylbenzamide
• 英文别名: N-(3-cyano-2,4,6-trimethylphenyl)-2,4,6-trimethylbenzamide
• 化学式: C₂₀H₂₂N₂O
• 分子量: 306.407
• InChiKey: KNOZHGBMHZYFGF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.66
• 重原子数：
  23.0
• 可旋转键数：
  2.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  52.89
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  2,4,6-三甲基苯甲腈 在 氟磺酸 、 lead dioxide 、 盐酸 、 水 作用下， 反应 5.0h， 以94%的产率得到N-(2,4,6-trimethyl-3-cyanophenyl)-2,4,6-trimethylbenzamide
  参考文献：
  名称：

  摘要：

  The yield of products formed by low-temperature oxidation of methylbenzonitriles with PbO2 in fluorosulfonic acid solutions was studied in relation to the stabilization factor of the reaction system. The revealed correlation is common for methylbenzonitriles differing in the degree of alkylation and in the oxidation mechanism.

  DOI：

  10.1023/a:1024901819045

文献信息

• Rudenko; Salfetnikova; Vasil'ev, Russian Journal of Organic Chemistry, 1996, vol. 32, # 10, p. 1447 - 1470
  作者：Rudenko、Salfetnikova、Vasil'ev

  DOI：——

  日期：——
• Rudenko; Pragst, Russian Journal of Organic Chemistry, 1998, vol. 34, # 11, p. 1589 - 1626
  作者：Rudenko、Pragst

  DOI：——

  日期：——
• ——
  作者：S. I. Kol'tsov、Yu. N. Salfetnikova

  DOI：10.1023/a:1024901819045

  日期：——

  The yield of products formed by low-temperature oxidation of methylbenzonitriles with PbO2 in fluorosulfonic acid solutions was studied in relation to the stabilization factor of the reaction system. The revealed correlation is common for methylbenzonitriles differing in the degree of alkylation and in the oxidation mechanism.