3-(cyclohexanemethyl)amino-1-propanesulfonic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: 3-(cyclohexanemethyl)amino-1-propanesulfonic acid
• 英文别名: 3-(Cyclohexylmethylamino)propane-1-sulfonic acid
• 化学式: C₁₀H₂₁NO₃S
• 分子量: 235.348
• InChiKey: JEQMISOAJKZABI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  74.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1,3-丙烷磺内酯 、 环己甲胺 以 乙腈 为溶剂， 反应 2.0h， 以81%的产率得到3-(cyclohexanemethyl)amino-1-propanesulfonic acid
  参考文献：
  名称：

  [EN] METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES
  [FR] METHODES ET COMPOSITIONS POUR TRAITER LES MALADIES LIEES A L'AMYLOIDE

  摘要：

  公开号：

  WO2004113275A3

文献信息

• Methods and compositions for treating amyloid-related diseases
  申请人：Kong Xianqi

  公开号：US20050096385A1

  公开（公告）日：2005-05-05

  Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.

  本文描述了用于治疗或预防与淀粉样蛋白相关疾病的方法、化合物、药物组合物和试剂盒。
• METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES
  申请人：Kong Xianqi

  公开号：US20100113591A1

  公开（公告）日：2010-05-06

  Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.

  本发明涉及用于治疗或预防淀粉样蛋白相关疾病的方法、化合物、制药组合物和试剂盒。
• POLYISOCYANATE MODIFIED WITH SULPHAMIC ACID, PREPARATION METHOD THEREFOR AND USE THEREOF
  申请人：Wanhua Chemical Group Co., Ltd.

  公开号：EP3045485A1

  公开（公告）日：2016-07-20

  A polyisocyanate modified with sulphamic acid and a mixture thereof, the preparation method thereof, and the use thereof in the production of polyurethane, especially as a cross-linking ingredient in the field of aqueous coatings and adhesives containing groups that are capable of reacting with isocyanate groups.

  一种用氨基磺酸改性的多异氰酸酯及其混合物，其制备方法，以及在聚氨酯生产中的用途，特别是作为水性涂料和粘合剂领域中的交联成分，含有能与异氰酸酯基团反应的基团。
• POLYISOCYANATE COMPOSITION, COATING COMPOSITION AND COATING SUBSTRATE
  申请人：Asahi Kasei Kabushiki Kaisha

  公开号：EP3778686A1

  公开（公告）日：2021-02-17

  A polyisocyanate composition includes a polyisocyanate containing a sulfonic acid anion group in a molecule, a tertiary ammonium cation of an amine compound, and a uretdione dimer and isocyanurate trimer of a diisocyanate monomer, wherein the tertiary ammonium cation of the amine compound includes a tertiary ammonium cation of one or more amine compounds represented by general formula (1), a content of the uretdione dimer is 2.0% by mass or more and 20.0% by mass or less with respect to a total mass of the composition, and a content of a uretdione dimer containing a sulfonic acid anion group in a molecule is 0.15% by mass or less with respect to a total mass of the polyisocyanate containing a sulfonic acid anion group in a molecule, the uretdione dimer and the isocyanurate trimer.

  一种多异氰酸酯组合物包括分子中含有磺酸阴离子基团的多异氰酸酯、胺化合物的叔铵盐阳离子以及二异氰酸酯单体的脲二酮二聚体和异氰尿酸酯三聚体、 其中胺化合物的叔铵阳离子包括通式(1)代表的一种或多种胺化合物的叔铵阳离子、 脲二酮二聚体的含量占组合物总质量的 2.0%（以质量计）或以上，20.0%（以质量计）或以下，以及 相对于分子中含有磺酸阴离子基团的多异氰酸酯、脲二酮二聚体和异氰尿酸酯三聚体的总质量而言，分子中含有磺酸阴离子基团的脲二酮二聚体的含量为 0.15%（以质量计）或更少。
• POLYISOCYANATE COMPOSITION, COATING COMPOSITION AND COATING BASE MATERIAL
  申请人：Asahi Kasei Kabushiki Kaisha

  公开号：EP3878838A1

  公开（公告）日：2021-09-15

  The present invention provides a polyisocyanate composition comprising a polyisocyanate having a sulfonic acid anion group in its molecule and a tertiary ammonium cation of an amine compound, wherein the tertiary ammonium cation of an amine compound includes a tertiary ammonium cation of at least one amine compound selected from amine compounds represented by the following general formulas (1) and (2), and an amount of the tertiary ammonium cation of the selected amine compound is 70 mol% or more with respect to a total molar amount of the tertiary ammonium cation of all amine compounds in the composition.

  本发明提供了一种多异氰酸酯组合物，该组合物包含在其分子中具有磺酸阴离子基团的多异氰酸酯和胺化合物的叔铵阳离子，其中胺化合物的叔铵阳离子包括至少一种选自以下通式(1)和(2)所代表的胺化合物的叔铵阳离子、所选胺化合物的叔铵阳离子的量占组合物中所有胺化合物的叔铵阳离子总摩尔量的 70 摩尔%或以上。