钠离子载体V | 129880-73-5

• 物质功能分类: 分析化学 - 分析试剂 - 常用分析试剂
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 钠离子载体V
• 中文别名: 4-十八烷酸甲基-N,N,N′,N′-四环己基-1,2-苯二氧基二乙酰胺
• 英文名称: 3,4-Bis(2-(dicyclohexylamino)-2-oxoethoxy)benzyl stearate
• 英文别名: [3,4-bis[2-(dicyclohexylamino)-2-oxoethoxy]phenyl]methyl octadecanoate
• CAS: 129880-73-5
• 化学式: C₅₃H₈₈N₂O₆
• 分子量: 849.3
• InChiKey: HSRJLFJSCKIVPQ-UHFFFAOYSA-N

物化性质

• 闪点：
  -4 °C

计算性质

• 辛醇/水分配系数(LogP)：
  16.3
• 重原子数：
  61
• 可旋转键数：
  29
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  85.4
• 氢给体数：
  0
• 氢受体数：
  6

安全信息

• 危险品标志：
  F,N,Xn
• 安全说明：
  S16,S33,S60,S61,S62
• 危险类别码：
  R11,R38,R50/53,R65,R67
• WGK Germany：
  1,2

反应信息

• 作为产物：
  描述：

  N,N,N',N'-tetrakis-(cyclohexyl)-4-hydroxymethyl-1,2-phenylenedioxydiacetamide 、 十八烷酰氯 以51%的产率得到
  参考文献：
  名称：

  GEHRIG, P.;RUSTERHOLZ, B.;SIMON, W., ANAL. CHIM. ACTA , 233,(1990) N, C. 295-298

  摘要：

  DOI：

文献信息

• Microsphere optical ion sensors based on doped silica gel templates
  申请人：Bakker Eric

  公开号：US20060240560A1

  公开（公告）日：2006-10-26

  A sensor for determining the concentration of a target ion in a liquid sample having a particulate silica doped with: an ionophore capable of binding the target ion; and an indicator capable of producing a detectable signal in response to binding by the ionophore of the target ion. The detectable signal is related to the target ion concentration in the liquid sample.

  一种用于测定液体样品中目标离子浓度的传感器，其中包含掺杂有颗粒状的二氧化硅，其中包含：能够结合目标离子的离子载体；以及能够在离子载体结合目标离子的响应下产生可检测信号的指示剂。可检测信号与液体样品中目标离子的浓度相关。
• Material for establishing solid state contact for ion selective electrodes
  申请人：Ciba Corning Diagnostics Corp.

  公开号：EP0643299A1

  公开（公告）日：1995-03-15

  A polymeric material which to form a stable, reproducible interface between the ionic and electronic domains of an ion selective sensor, or an ion selective field effect transistor, or the like is provided. When employed in an ion selective sensor, the polymeric material is advantageously provided over a solid internal reference electrode and an ion selective material is provided thereover. According to one embodiment, the polymeric material of the invention includes less than about 1.63 x 10²¹ immobilized charged sites per gram (less than about 2.72 millaequivalents/gram). According to another embodiment, the polymeric material includes immobilized sites of charge opposite that of mobile ions involved in the redox couple. A preferred polymeric material comprises a copolymer of methacrylamidopropyltrimethylammoniumchloride and methylmethacrylate.

  提供了一种聚合物材料，可在离子选择传感器或离子选择场效应晶体管等的离子域和电子域之间形成稳定、可重复的界面。在离子选择性传感器中使用时，聚合物材料最好覆盖在固体内部参比电极上，并在其上提供离子选择性材料。根据一个实施方案，本发明的聚合物材料包括每克小于约 1.63 x 10²¹ 固定带电位点（小于约 2.72 毫当量/克）。根据另一个实施方案，聚合物材料包括与参与氧化还原反应的移动离子电荷相反的固定电荷位点。一种优选的聚合物材料包括甲基丙烯酰胺丙基三甲基氯化铵和甲基丙烯酸甲酯的共聚物。
• POTENTIOMETRIC SENSOR FOR THE QUANTITATIVE DETERMINATION OF SODIUM CONCENTRATION AND CREATININE CONCENTRATION
  申请人：Medizinische Universität Innsbruck

  公开号：EP3388825A1

  公开（公告）日：2018-10-17

  The present invention relates to a single-use test-strip for the quantitative determination of sodium concentration and creatinine concentration and for the subsequent determination of their ratio, and to a non-invasive point-of-care (POC) device for detecting sodium depletion and/or sodium overload in a patient's body. Furthermore, the present invention relates to a method for simultaneously and quantitatively determining sodium concentration and creatinine concentration in a patient's urine sample and to a method of detecting sodium depletion and/or sodium overload in a patient's body.

  本发明涉及一种用于定量测定钠浓度和肌酐浓度并随后测定其比率的一次性试纸，以及一种用于检测患者体内钠耗竭和/或钠超负荷的非侵入性护理点（POC）设备。此外，本发明还涉及一种同时定量测定患者尿样中钠浓度和肌酐浓度的方法，以及一种检测患者体内钠耗竭和/或钠超负荷的方法。
• MEANS FOR THE QUANTITATIVE DETERMINATION OF AN ANALYTE CONCENTRATION IN A PATIENT'S URINE SAMPLE
  申请人：Fuhrmann, Gerda Laura

  公开号：EP3537153A1

  公开（公告）日：2019-09-11

  The present invention relates to a single-use monoanalytical test-strip for the quantitative determination of an analyte in a patient's urine sample, and to a non-invasive point-of-care (POC) device for detecting deficiency and/or overload of an analyte in a patient's body. Furthermore, the present invention relates to a method for quantitatively determining the concentration of an analyte in a patient's urine sample and to a method of detecting deficiency and/or overload of an analyte in a patient's body. The test-strip comprises a substrate which either is electrically insulating or which has an electrically insulating layer applied thereon,- an electrode assembly applied on said substrate or on said electrically insulating layer, if present; and said electrode assembly comprises at least- one analyte-selective working electrode;- one reference electrode for said analyte-selective working electrode and an interface for electrically connecting said electrode assembly to a read out-meter device. Analytes are anions selected from halides, phopshates and sulfates or cations of alkali metals, of alkaline earth metals or of other metals.

  本发明涉及一种用于定量测定患者尿样中分析物的一次性单分析试纸，以及一种用于检测患者体内分析物缺乏和/或过量的非侵入性护理点（POC）设备。此外，本发明还涉及一种定量测定患者尿样中分析物浓度的方法，以及一种检测患者体内分析物缺乏和/或过量的方法。检测条包括一个基板，该基板是电绝缘的，或者在其上涂有电绝缘层；- 一个电极组件，如果有的话，涂在所述基板上或所述电绝缘层上；所述电极组件包括至少--一个分析物选择性工作电极；--一个用于所述分析物选择性工作电极的参比电极，以及一个用于将所述电极组件电连接到读出计装置的接口。分析物为阴离子，选自卤化物、磷酸盐和硫酸盐或碱金属、碱土金属或其他金属的阳离子。
• Systems and methods for detecting an optical change indicating the presence of an analyte
  申请人：Case Western Reserve University

  公开号：US10393665B2

  公开（公告）日：2019-08-27

  One aspect of the present disclosure relates to an analyte sensor device. The analyte sensor device can include an optode layer that undergoes an optical change in the presence of an analyte. The analyte sensor device can also include a selectively-permeable membrane encapsulating the optode layer to form a stable membrane that that minimizes fouling of the analyte sensor device. The analyte sensor device can also include a plurality of microparticles that suppress a background physical interference on a detection of the optical change of the optode layer.

  本公开的一个方面涉及一种分析物传感器装置。分析物传感器装置可以包括一个光电极层，在分析物存在的情况下，光电极层会发生光学变化。分析物传感器装置还可以包括封装光电极层的选择性渗透膜，以形成稳定的膜，最大限度地减少分析物传感器装置的堵塞。分析物传感器装置还可以包括多个微颗粒，以抑制背景物理干扰对光极层光学变化的检测。