[(2R)-3-carboxy-2-[(Z)-dec-4-enoyl]oxypropyl]-trimethylazanium | 1256380-16-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: [(2R)-3-carboxy-2-[(Z)-dec-4-enoyl]oxypropyl]-trimethylazanium
• CAS: 1256380-16-1
• 化学式: C17H32NO4+
• 分子量: 314.4
• InChiKey: OQWOHRPOYAVIOK-FJVVXJACSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  22
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.76
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Compositions comprising omega-3 polyunsaturated and medium chain fatty acids
  申请人：Hill's Pet Nutrition, Inc.

  公开号：US10973244B2

  公开（公告）日：2021-04-13

  Disclosed herein are pet food compositions for treating or preventing inflammation or an inflammatory disorder in an animal comprising an effective amount of at least one medium chain triglyceride and an effective amount of at least one omega-3 fatty acid, wherein the at least one medium chain triglycride and the at least one omega-3 fatty acid are present in an amount effect to a provide a synergistic decrease in the amount of circulating cytokines in the companion animal. Also disclosed herein are methods for treating or preventing inflammation or an inflammatory disorder in a companion animal, comprising administering the pet food compositions disclosed herein to the companion animal in need thereof.

  本文公开了用于治疗或预防动物炎症或炎症性疾病的宠物食品组合物，该组合物包含有效量的至少一种中链甘油三酯和有效量的至少一种ω-3脂肪酸，其中至少一种中链甘油三酯和至少一种ω-3脂肪酸的存在量可协同降低伴侣动物体内循环细胞因子的量。本文还公开了治疗或预防伴侣动物炎症或炎症性疾病的方法，包括向需要的伴侣动物施用本文公开的宠物食品组合物。
• Compositions Comprising Omega-3 Polyunsaturated and Medium Chain Fatty Acids
  申请人：Hill's Pet Nutrition, Inc.

  公开号：US20200296996A1

  公开（公告）日：2020-09-24

  Disclosed herein are pet food compositions for treating or preventing inflammation or an inflammatory disorder in an animal comprising an effective amount of at least one medium chain triglyceride and an effective amount of at least one omega-3 fatty acid, wherein the at least one medium chain triglycride and the at least one omega-3 fatty acid are present in an amount effect to a provide a synergistic decrease in the amount of circulating cytokines in the companion animal. Also disclosed herein are methods for treating or preventing inflammation or an inflammatory disorder in a companion animal, comprising administering the pet food compositions disclosed herein to the companion animal in need thereof.
• COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF CONDITIONS RELATED TO THE QUALITY OF AGING AND LONGEVITY
  申请人：Epitracker, Inc.

  公开号：US20210052535A1

  公开（公告）日：2021-02-25

  Compositions including metabolites that are small molecules, and salts and derivatives thereof, and methods for treatment or prophylaxis of conditions related to the quality of aging are provided, including compositions and methods for treating conditions that negatively impact longevity and the quality of aging, including inflammation, anemia, hyperglycemia, dyslipidemia, hyperinsulinemia, liver disease, iron overload, impaired skin integrity, wound healing, scarring, pain, allergies, sleep disorders and problems, and gastrointestinal disorders and problems.
• BIOMARKERS AND USES THEREOF FOR DIAGNOSING THE SILENT PHASE OF ALZHEIMER'S DISEASE
  申请人：AgenT

  公开号：US20210325409A1

  公开（公告）日：2021-10-21

  The present invention relates to a molecular signature of the silent phase of Alzheimer's disease; and to methods using the same, for diagnosing a silent stage of Alzheimer's disease in a subject, stratifying a silent phase of Alzheimer's disease in a subject into different grades of the silent phase, prognosticating the progress of a silent phase of Alzheimer's disease in a subject, and determining a personalized course of treatment in a subject affected with a silent phase of Alzheimer's disease, it also relates to a computer system comprising a machine learning algorithm trained for diagnosing a silent phase of Alzheimer's disease in a subject.
• Pet Food Compositions Comprising Caprylic Acid and Docosahexaenoic Acid and/or Eicosapetaenoic Acid for Use in Treating Struvite Urolithiasis
  申请人：Hill's Pet Nutrition, Inc.

  公开号：US20220202759A1

  公开（公告）日：2022-06-30

  Disclosed herein are pet food compositions for treating or preventing—inter alia—struvite urolithiasis comprising at N least one of caprylic acid and capric acid; and at least one of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA).