2-benzoyl-1-tert-butyl-1-(3,4-dichlorobenzoyl)hydrazine | 112226-22-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-benzoyl-1-tert-butyl-1-(3,4-dichlorobenzoyl)hydrazine
• 英文别名: N'-t-butyl-N-benzoyl-N'-(3,4-dichlorobenzoyl)hydrazine；N'-benzoyl-N-tert-butyl-3,4-dichlorobenzohydrazide
• CAS: 112226-22-9
• 化学式: C₁₈H₁₈Cl₂N₂O₂
• 分子量: 365.259
• InChiKey: HOMNKNDCTNDEBU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  49.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3,4-二氯苯甲酸 在 sodium hydroxide 、 氯化亚砜 作用下， 以 乙醚 为溶剂， 反应 15.0h， 生成 2-benzoyl-1-tert-butyl-1-(3,4-dichlorobenzoyl)hydrazine
  参考文献：
  名称：

  Quantitative structure-activity analysis of larvicidal 1-(substituted benzoyl)-2-benzoyl-1-tert-butylhydrazines againstChilo suppressalis

  摘要：

  AbstractThe larvicidal activity of a number of 1‐(substituted benzoyl)‐2‐benzoyl–1 ‐ten‐butylhydrazines against the rice stem borer (Chilo suppressalis Walk.) was measured. Variations in the activity were examined quantitatively using physico‐chemical substituent and molecular parameters and regression analysis. The results indicated that the molecular hydrophobicity and the electron‐withdrawing inductive/ field effect of ontho substituents are favourable to larvicidal activity. The bulkiness of substituents at the meta and para positions was unfavourable to activity, substitution at the para position being more unfavourable than that at the meta position in terms of van der Waals' volume. The 2,3–, 2,5‐ and 2,6‐disubstitution patterns were also unfavourable to activity. Reductions in larvicidal activity caused by the 2,6‐,‐ 2,3,5‐ and 2,3,4,5‐substitutions were greater than those induced by the 2,3‐ and 2,5‐disubstitutions. When the sum of contributions from favourable effects is greater than that from unfavourable effects, the larvicidal activity is expected to be superior to that of the unsubstituted compound.

  DOI：

  10.1002/ps.2780410210

文献信息

• Insecticidal substituted and unsubstituted benzoic acid 1-alkyl, 2 alkyl
  申请人：American Cyanamid Company

  公开号：US04814349A1

  公开（公告）日：1989-03-21

  The present invention relates to methods for controlling insect populations and for protecting living plants from insect attack by applying to said plants or to the soil in which they are growin an insecticidally-effective amount of a substituted benzoic acid 1 or 2-alkyl or 2-cycloalkylhydrazide. Novel substituted benzoic acid 1 and 2-alkyl and 2-cycloalkylhydrazides effective as insecticides or intermediates for the preparation of insecticidal diacylhydrazides also are presented.

  本发明涉及通过向植物或它们生长的土壤施加一定量的取代苯甲酸1或2-烷基或2-环烷基脒来控制昆虫种群和保护植物免受昆虫侵袭的方法。还提供了作为杀虫剂或用于制备杀虫二酰基脒的中间体的新型取代苯甲酸1和2-烷基以及2-环烷基脒。
• Method for making hydrazide or hydrazine compounds
  申请人：American Cyanamid Company

  公开号：US05300688A1

  公开（公告）日：1994-04-05

  This invention relates to the preparation of hydrazide or hydrazine compounds. More particularly, this invention relates to an efficient method for the preparation of substituted hydrazides, hydrazines, and intermediates therefor, from urea starting products. Such hydrazide and hydrazine compounds are useful as insecticides.

  本发明涉及制备肼或肼类化合物。更具体地说，本发明涉及一种从尿素起始物制备取代肼酰和肼类化合物及其中间体的高效方法。这种肼酰和肼类化合物可以用作杀虫剂。
• Insecticidal substituted and unsubstituted benzoic acid 1-alkyl, 2-alkyl
  申请人：American Cyanamid Company

  公开号：US05237099A1

  公开（公告）日：1993-08-17

  The present invention relates to methods for controlling insect populations and for protecting living plants from insect attack by applying to said plants or to the soil in which they are growing an insecticidally-effective amount of a substituted benzoic acid 1 or 2-alkyl or 2-cycloalkylhydrazide. Novel substituted benzoic acid 1 and 2-alkyl and 2-cycloalkylhydrazides effective as insecticides or intermediates for the preparation of insecticidal diacylhydrazides also are presented.

  本发明涉及一种控制昆虫种群和保护植物免受昆虫攻击的方法，该方法是通过向这些植物或它们所生长的土壤中施加一定量的取代苯甲酸1或2-烷基或2-环烷基腙来实现的。本发明还提供了一种新型的取代苯甲酸1和2-烷基以及2-环烷基腙，它们具有杀虫剂作用或用于制备杀虫双酰肼的中间体。
• Insecticidal N'-substituted-N,N'-diacylhydrazines
  申请人：ROHM AND HAAS COMPANY

  公开号：EP0236618A2

  公开（公告）日：1987-09-16

  This invention is concerned with insecticidal compositions containing N'-substituted-N,N'-diacylhydrazines, methods of using such compositions and with certain of the insecticidal N'-substituted-N,N'-diacylhydrazines which are novel compounds.

  本发明涉及含有 N'-取代-N,N'-二乙酰肼的杀虫组合物、使用此类组合物的方法以及某些杀虫 N'-取代-N,N'-二乙酰肼的新型化合物。
• Novel insecticidal diacylhydrazine compounds
  申请人：AMERICAN CYANAMID COMPANY

  公开号：EP0228564B1

  公开（公告）日：1992-01-29