Homoarginine methyl ester

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Homoarginine methyl ester
• 英文别名: methyl (2S)-2-amino-6-(diaminomethylideneamino)hexanoate
• 化学式: C₈H₁₈N₄O₂
• 分子量: 202.25
• InChiKey: NBQATONWNUGXKD-LURJTMIESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  117
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• [EN] N-METHYL AMINO ACIDS<br/>[FR] ACIDES N-METHYL AMINES
  申请人：UBIQUITOUS TECHNOLOGIES PTY LT

  公开号：WO2004007427A1

  公开（公告）日：2004-01-22

  The present invention relates to a compound of formula (I) or (II), processes for preparing them, peptides including them and kits involving them.

  这项发明涉及到式(I)或(II)的化合物，制备它们的方法，包括它们的肽和涉及它们的试剂盒。
• EP1575900A4
  申请人：——

  公开号：EP1575900A4

  公开（公告）日：2007-02-21
• N-METHYL AMINO ACIDS
  申请人：UBIQUITOUS TECHNOLOGIES PTY LTD

  公开号：EP1575900A1

  公开（公告）日：2005-09-21
• COMPOSITIONS COMPRENANT DES LIPOPHOSPHORAMIDES ET LEURS UTILISATIONS EN THERAPIE GENIQUE
  申请人：Universite de Bretagne Occidentale

  公开号：EP2193204B1

  公开（公告）日：2011-08-31
• NOVEL LIPOPHILIC COMPOSITIONS AND USES THEREOF
  申请人：Clement Jean-Claude

  公开号：US20110008415A1

  公开（公告）日：2011-01-13

  New co-lipids for use in combination with lipophilic compounds as nucleic acid vectors, for preparing a nucleic acid vector composition, and methods for introducing in vitro or in vivo a nucleic acid of interest into host cells, including a step of contacting host cells these nucleic acid vector compositions. The nucleic acid vector compositions have the combination (i) of a nucleic acid, cationic, lipophilic vector with (ii) a co-lipid. These nucleic acid vector compositions, in some embodiments, are present in the form of unilamellar or multilamellar vesicles.