2-benzylsuccinyl-CoA

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-benzylsuccinyl-CoA
• 英文别名: 4-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethylsulfanyl]-3-benzyl-4-oxobutanoic acid
• 化学式: C₃₂H₄₆N₇O₁₉P₃S
• 分子量: 957.7
• InChiKey: KIRGTNPWUTXDFF-OUDFDEKCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.2
• 重原子数：
  62
• 可旋转键数：
  25
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  426
• 氢给体数：
  10
• 氢受体数：
  24

文献信息

• MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE
  申请人：Osterhout Robin E.

  公开号：US20120021478A1

  公开（公告）日：2012-01-26

  The invention provides non-naturally occurring microbial organisms having a toluene, benzene, p-toluate, terephthalate, (2-hydroxy-3-methyl-4-oxobutoxy)phosphonate, (2-hydroxy-4-oxobutoxy)phosphonate, benzoate, styrene, 2,4-pentadienoate, 3-butene-1ol or 1,3-butadiene pathway. The invention additionally provides methods of using such organisms to produce toluene, benzene, p-toluate, terephthalate, (2-hydroxy-3-methyl-4-oxobutoxy)phosphonate, (2-hydroxy-4-oxobutoxy)phosphonate, benzoate, styrene, 2,4-pentadienoate, 3-butene-1ol or 1,3-butadiene.

  本发明提供了一种非自然出现的微生物有甲苯、苯、对甲苯酸、对苯二甲酸、(2-羟基-3-甲基-4-氧代丁氧基)膦酸酯、(2-羟基-4-氧代丁氧基)膦酸酯、苯甲酸、苯乙烯、2,4-戊二烯酸、3-丁烯-1-醇或1,3-丁二烯代谢途径。此外，本发明还提供了使用这些微生物制备甲苯、苯、对甲苯酸、对苯二甲酸、(2-羟基-3-甲基-4-氧代丁氧基)膦酸酯、(2-羟基-4-氧代丁氧基)膦酸酯、苯甲酸、苯乙烯、2,4-戊二烯酸、3-丁烯-1-醇或1,3-丁二烯的方法。
• Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
  申请人：Genomatica, Inc.

  公开号：EP2607340A1

  公开（公告）日：2013-06-26

  The invention provides non-naturally occurring microbial organisms having a 1,3-butadiene pathway. The invention additionally provides methods of using such organisms to produce 1,3-butadiene.

  本发明提供了具有 1,3-丁二烯途径的非天然微生物。此外，本发明还提供了利用此类生物生产 1,3-丁二烯的方法。
• MICROORGANISMS AND METHODS FOR THE PRODUCTION OF 1.4- CYCLOHEXANEDIMETHANOL
  申请人：Genomatica, Inc.

  公开号：EP2652141A1

  公开（公告）日：2013-10-23
• MICROORGANISMS AND METHODS FOR THE PRODUCTION OF 1,4-CYCLOHEXANEDIMETHANOL
  申请人：PHARKYA Priti

  公开号：US20120156740A1

  公开（公告）日：2012-06-21

  A non-naturally occurring microbial organism includes a microbial organism having a 1,4-cyclohexanedimethanol pathway that includes at least one exogenous nucleic acid encoding a 1,4-cyclohexanedimethanol pathway enzyme expressed in a sufficient amount to produce 1,4-cyclohexanedimethanol. A method for producing 1,4-cyclohexanedimethanol includes culturing a non-naturally occurring microbial organism having a 1,4-cyclohexanedimethanol pathway. The pathway includes at least one exogenous nucleic acid encoding a 1,4-cyclohexanedimethanol pathway enzyme expressed in a sufficient amount to produce 1,4-cyclohexanedimethanol, under conditions and for a sufficient period of time to produce 1,4-cyclohexanedimethanol.
• US8715957B2
  申请人：——

  公开号：US8715957B2

  公开（公告）日：2014-05-06