(4S,4aS)-1-氨基-7-乙烯基-4,7-二甲基-4,4a,5,6-四氢吡咯并[5,1-f]嘧啶-3-酮 | 35471-10-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 中文名称: (4S,4aS)-1-氨基-7-乙烯基-4,7-二甲基-4,4a,5,6-四氢吡咯并[5,1-f]嘧啶-3-酮
• 英文名称: 1-Amino-7-vinyl-4a,5,6,7-tetrahydro-4,7-dimethylpyrrolo[1,2-c]pyrimidin-3(4H)-one
• 英文别名: 7-ethenyl-1-imino-4,7-dimethyl-4,4a,5,6-tetrahydropyrrolo[1,2-c]pyrimidin-3-one
• CAS: 35471-10-4
• 化学式: C₁₁H₁₇N₃O
• 分子量: 207.27
• InChiKey: JICZMZVYTMAXGX-UHFFFAOYSA-N

物化性质

• 熔点：
  20B-210°C
• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  58.7
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Extracts of Curcuma and Methods of Use Thereof
  申请人：Alberte Randall S.

  公开号：US20100098788A1

  公开（公告）日：2010-04-22

  The present invention relates in part to turmeric extracts that are useful for treating or preventing neurodegenerative disorders. Another aspect of the invention relates in part to turmeric extracts that are useful for treating or preventing inflammatory disorders. In some embodiments, the extracts comprise at least one compound selected from the group consisting of 25 to 500 μg bamosamine, 25 to 750 μg echinaxanthol, 100 to 3,000 μg bisdemethoxycurcumin, 50 to 500 μg daphniyunnine E and 500 to 75,000 μg curcumin per 100 mg of extract. Another aspect of the invention relates to pharmaceutical compositions comprising the aforementioned extracts. Another aspect of the invention relates to methods of treating or preventing neurodegenerative disorders comprising administering to a subject in need thereof an effective amount of the aforementioned extracts or compositions. Another aspect of the invention relates to methods of making the aforementioned extracts.

表征谱图