(E)-12-羟基十八碳-9-烯酰胺 | 35732-94-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: (E)-12-羟基十八碳-9-烯酰胺
• 英文名称: [r-(z)]-12-Hydroxy-9-octadecenamide
• 英文别名: (Z,12R)-12-hydroxyoctadec-9-enamide
• CAS: 35732-94-6
• 化学式: C₁₈H₃₅NO₂
• 分子量: 297.5
• InChiKey: VSKRSEHLMRRKOS-QJWNTBNXSA-N

物化性质

• 熔点：
  64-65.5 °C
• 沸点：
  476.7±28.0 °C(Predicted)
• 密度：
  0.935±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  21
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  63.3
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 海关编码：
  2924199090

文献信息

• SKIN AGENT FOR EXTERNAL USE AND COSMETIC AGENT INCLUDING UBIQUINONE DERIVATIVE OR SALT THEREOF AND METHOD USING THE SAME
  申请人：Aoki Hirobumi

  公开号：US20100074879A1

  公开（公告）日：2010-03-25

  A skin agent for external use and a cosmetic agent are provided, by transdermal administration of which expected actions and effects of ubiquinone derivatives, salts thereof, ubiquinones and ubiquinols are effectively obtained. The skin agent for external use includes a ubiquinone derivative or a salt thereof as an active ingredient. The ubiquinone derivative is represented by the formula (1): wherein R 1 and R 2 are each a hydrogen atom or a phosphoric group, at least one of R 1 and R 2 is a phosphoric group, and n is an integer in the range of 1 to 9.

  提供了一种外用皮肤剂和化妆品剂，通过经皮给药，可以有效地获得辅酶Q衍生物、其盐、辅酶Q和辅酶QH的预期作用和效果。外用皮肤剂包括辅酶Q衍生物或其盐作为活性成分。辅酶Q衍生物由式（1）表示：其中R1和R2分别是氢原子或磷酸基团，R1和R2中至少有一个是磷酸基团，n是1到9范围内的整数。
• [EN] PERSONAL CARE COMPOSITIONS COMPRISING FATTY ACID AMIDE DERIVATIVES<br/>[FR] COMPOSITIONS DE SOIN PERSONNEL COMPRENANT DES DÉRIVÉS D'AMIDES D'ACIDE GRAS
  申请人：UNILEVER PLC

  公开号：WO2018019463A1

  公开（公告）日：2018-02-01

  In one embodiment, the present invention provides a personal care composition, comprising: (i) a compound of Formula (1) at a concentration from 0.0001 wt % to 20 wt % of the composition; wherein R is selected from the group consisting of C15-C23 conjugated dienes, C15-C23 hydroxylated mono unsaturated alkenes, and C15-C23 hydroxylated alkanes; wherein R1 is selected from the group consisting of H, C1-C4 alkyl, - CH2OH, -CH2(CH3)-OH,-[CH2]4-NH2, -CH2-CO2H, -[CH2]2-CO2H, (I), (II) and (III); wherein R3 is -CO2H; -CH2CO2H; -CH2CH2CO2H;; and (ii) a cosmetically acceptable carrier.

  在一个实施例中，本发明提供一种个人护理组合物，包括：(i) 按照浓度为0.0001重量%至20重量%的组合物的公式(1)的化合物；其中R从C15-C23共轭二烯烃、C15-C23羟基单不饱和烯烃和C15-C23羟基烷烃组成的群体中选择；其中R1从H、C1-C4烷基、- CH2OH、-CH2(CH3)-OH、-[CH2]4-NH2、-CH2-CO2H、-[CH2]2-CO2H、(I)、(II)和(III)组成的群体中选择；其中R3为-CO2H；-CH2CO2H；-CH2CH2CO2H；；和(ii) 一种化妆品可接受的载体。
• Tailored Oils Produced from Recombinant Oleaginous Microorganisms
  申请人：Franklin Scott

  公开号：US20120203018A1

  公开（公告）日：2012-08-09

  Methods and compositions for the production of oil, fuels, oleochemicals, and other compounds in recombinant microorganisms are provided, including oil-bearing microorganisms and methods of low cost cultivation of such microorganisms. Microalgal cells containing exogenous genes encoding, for example, a lipase, a sucrose transporter, a sucrose invertase, a fructokinase, a polysaccharide-degrading enzyme, a keto acyl-ACP synthase enzyme, a fatty acyl-ACP thioesterase, a fatty acyl-CoA/aldehyde reductase, a fatty acyl-CoA reductase, a fatty aldehyde reductase, a fatty acid hydroxylase, a desaturase enzyme, a fatty aldehyde decarbonylase, and/or an acyl carrier protein are useful in manufacturing transportation fuels such as renewable diesel, biodiesel, and renewable jet fuel, as well as oleochemicals such as functional fluids, surfactants, soaps and lubricants.

  本文提供了用于在重组微生物中生产油、燃料、油脂化学品和其他化合物的方法和组合物，包括含油微生物和低成本培养这种微生物的方法。含有外源基因编码脂肪酶、蔗糖转运蛋白、蔗糖转化酶、果糖激酶、多糖降解酶、酮基酰基-ACP合酶酶、脂肪酰-ACP硫酯酶、脂肪酰-CoA/醛还原酶、脂肪酰-CoA还原酶、脂肪醛还原酶、脂肪酸羟化酶、不饱和酶、脂肪醛脱羰基酶和/或酰基载体蛋白的微藻细胞可用于制造可再生柴油、生物柴油和可再生喷气燃料，以及油脂化学品，如功能流体、表面活性剂、肥皂和润滑剂。
• [EN] PROCESS FOR MANUFACTURING A CLEAVED PRODUCT FROM A RICINIC COMPOUND<br/>[FR] PROCÉDÉ DE FABRICATION D'UN PRODUIT CLIVÉ À PARTIR D'UN COMPOSÉ RICINIQUE
  申请人：SOLVAY

  公开号：WO2015011018A1

  公开（公告）日：2015-01-29

  The invention pertains to a method for manufacturing a cleaved product from a ricinic compound comprising reacting at a temperature of at least 150°C at least a ricinic compound and at least one alkali in the presence of at least one thinning agent selected from the group consisting of long chain phenol derivatives of formula (I) herein below; wherein: n and m, equal to or different from each other, are integers equal to 1, 2 or 3; p is zero or an integer of 1 to 3; RLong is a long-chain hydrocarbon group having 6 to 36 carbon atoms; RShort is a short-chain hydrocarbon group having 1 or 2 carbon atoms.

  本发明涉及一种从蓖麻化合物制造裂解产品的方法，包括在至少一种薄化剂的存在下，在至少150°C的温度下，使至少一种蓖麻化合物和至少一种碱反应，所述至少一种薄化剂选自以下式(I)的长链酚衍生物组中的至少一种；其中：n和m相等或不同，均为1、2或3的整数；p为0或1至3的整数；RLong是具有6到36个碳原子的长链烃基；RShort是具有1或2个碳原子的短链烃基。
• WHITENING DERMATOLOGICAL PREPARATIONS
  申请人：Kamachi Harumi

  公开号：US20090240070A1

  公开（公告）日：2009-09-24

  Disclosed is a dermatological preparation that are safe and are excellent in inhibiting and removing skin pigmentation and in inhibiting skin roughness. A dermatological preparation comprising a tocopherol aminoalkylcarboxylate and/or a salt thereof, the tocopherol aminoalkylcarboxylate being represented by Formula (I): wherein R 1 is a hydrogen atom or a lower alkyl group; R 2 and R 3 are each independently a hydrogen atom or a methyl group; X is a cycloalkylene group of 3 to 6 carbon atoms; and n is 0 or 1.

  本发明涉及一种皮肤科制剂，其安全有效地抑制和去除皮肤色素沉着，并抑制皮肤粗糙度。该皮肤科制剂包括一种生育酚氨基烷基羧酸酯和/或其盐，所述生育酚氨基烷基羧酸酯由式(I)表示：其中，R1是氢原子或低碳基；R2和R3各自独立地是氢原子或甲基基团；X是3至6个碳原子的环烷基团；n为0或1。