银(1+)5-氧代-2-吡咯烷羧酸酯 | 16205-01-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 银(1+)5-氧代-2-吡咯烷羧酸酯
• 英文名称: silver(I) 2-pyrrolidone-5-carboxylate
• 英文别名: [Ag(R-Hpyrrld)(S-Hpyrrld)]2；[silver(R,S)-2-pyrrolidone-5-carboxylate]2；[Ag(R,S-Hpyrrld)]2；[Ag(R-2-pyrrolidone-5-carboxylate)(S-2-pyrrolidone-5-carboxylate)]2；[Ag2(R-2-pyrrolidone-5-carboxylate)(S-2-pyrrolidone-5-carboxylate)]；[Ag((R,S)-2-pyrrolidone-5-carboxylate)]2；Silver(1+) 2-carboxy-3,4-dihydro-2H-pyrrol-5-olate；silver;(2S)-2-carboxy-3,4-dihydro-2H-pyrrol-5-olate
• CAS: 16205-01-9
• 化学式: 2Ag*2C₅H₆NO₃
• 分子量: 471.951
• InChiKey: QPHAHIAKNJDHGI-DFWYDOINSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -1.99
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  69.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  咪唑-4,5-二羧酸 、 银(1+)5-氧代-2-吡咯烷羧酸酯 以 水 为溶剂， 以90.2%的产率得到[silver(I)(imidazole-4,5-dicarboxylic acid-1H)]*0.25H2O
  参考文献：
  名称：

  Synthesis and molecular structures of a novel tetranuclear silver(I) cluster [Ag2(Himdc)(PPh3)2]2 (H3imdc = imidazole-4,5-dicarboxylic acid) and a mononuclear silver(I) complex [Ag(H2imdc)(PPh3)2]

  摘要：

  A novel tetranuclear silver(I) cluster, [Ag-2(Himdc)(PPh3)(2)](2) 1 (H(3)imdc = imidazole-4,5-dicarboxylic acid; O<^>N) was obtained by a reaction of the Ag-O bonding precursor [Ag(R-Hpyrrld)](2) (H(2)pyrrld = 2-pyrrolidone-5-carboxylic acid), PPh3 and H(3)mide. The mononuclear complex, [Ag(H(2)imdc)(PPh3)(2)](2), was also formed by the reactions using increased amounts of PPh3.In the solid state, complex I was a "bivalve"-like Ag-4 cluster, while complex 2 showed a supramolecular arrangement of the 4-coordinate AgP2(N<^>O) unit via the intermolecular hydrogen bonding interaction. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.inoche.2005.09.012
• 作为产物：
  描述：

  silver(l) oxide 、 L-焦谷氨酸 以 水 为溶剂， 以57.4%的产率得到银(1+)5-氧代-2-吡咯烷羧酸酯
  参考文献：
  名称：

  （R）-（+）-和（S）-（-）-2-吡咯烷酮-5-羧酸的水溶性银（I）配合物及其抗菌活性。通过二聚[Ag（Hpyrrld）] 2核自组装形成的固态手性螺旋聚合物和聚合物片结构

  摘要：

  的两种水溶性银（合成和表征我）络合物{[Ag（上- [R -Hpyrrld）] 2 } Ñ 1和{[银2（[R -Hpyrrld）（小号-Hpyrrld）]} Ñ 2 [ - [R -和描述了显示出广泛有效抗菌活性的S -H 2 pyrrld分别表示（R）-（+）-和（S）-（-）-2-吡咯烷酮-5-羧酸]，并确定了它们的晶体结构。单晶X射线分析揭示固态的1和2是右旋手性螺旋聚合物 和非手性 聚合物 分别由 自组装Ag 2（羧基-O，O '）2单位的单位[Ag–Ag 2.899（2）Å为1和2.875（2）Å为2 ; O形的Ag-O 160.3（5），163.2（5）°，1和163.1（2）°，2 ]。固态的1的螺旋度仅通过连接一个完成氧代基团在一个二聚体核心中与相邻的二聚体单元的银（I）中心之一相连。阐明了手性螺旋聚合物 图1是最近表征的对映体{[Ag（S- Hpyrrld）] 2 } n

  DOI：

  10.1039/b006552h

文献信息

• Syntheses, Structures, and Antimicrobial Activities of Remarkably Light-Stable and Water-Soluble Silver Complexes with Amino Acid Derivatives, Silver(I) <i>N</i>-Acetylmethioninates
  作者：Noriko Chikaraishi Kasuga、Rie Yoshikawa、Yoshitaka Sakai、Kenji Nomiya

  DOI：10.1021/ic201950p

  日期：2012.2.6

  prevents chelate formation of the ligand to the metal center, which is frequently observed in amino acid metal complexes, but allows for formation of hydrogen bonds between the ligands in the crystals of 1. These two silver(I) N-acetylmethioninates showed a wide spectrum of effective antimicrobial activities against Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa) and yeasts (Candida

  的反应升-和DL - ñ -acetylmethionine（Hacmet）和Ag 2 ö在水中于环境温度下，得到显着的光稳定的银络合物[Ag（上升-acmet）]} Ñ（1）和[银2（d -acmet）（l -acmet）]} n（2）分别。1和2的固体和水溶液的颜色在没有屏蔽的空气中，在超过1个月内没有变化。这两种银（I）配合物的光稳定性远高于蛋氨酸银（[Ag 2（d -met）（l -met）]} n（3）（Hmet =蛋氨酸），银（I）S-甲基-1-半胱氨酸盐[Ag（l -mecys）]} n（4）和银（ I）l-半胱氨酸Ag（l -Hcys）]} n（5）。通过蒸气扩散获得的1的X射线晶体学表明，形成具有两个O和两个S供体原子的梯状配位聚合物。acmet的乙酰基–可以防止在氨基酸金属络合物中经常观察到配体与金属中心的螯合形成，但是可以在1的晶体中的配体之间形成氢键。这两
• Synthesis of novel gold(I) complexes derived by AgCl-elimination between [AuCl(PPh3)] and silver(I) heterocyclic carboxylates, and their antimicrobial activities. Molecular structure of [Au(R,S-Hpyrrld)(PPh3)] (H2pyrrld = 2-pyrrolidone-5-carboxylic acid)
  作者：Ryusuke Noguchi、Akihiro Hara、Akiyoshi Sugie、Kenji Nomiya

  DOI：10.1016/j.inoche.2006.01.001

  日期：2006.4

  Abstract Novel gold(I) complexes with hard (O donor) and soft (P donor) Lewis bases, [Au(R,S-Hpyrrld)(PPh3)] · CHCl3 1 (H2pyrrld = 2-pyrrolidone-5-carboxylic acid) and [Au(R,S-othf)(PPh3)] 2 (Hothf = 5-oxo-2-tetrahydrofurancarboxylic acid), were prepared by the AgCl elimination reaction in CHCl3 between [AuCl(PPh3)] and the Ag–O bonding precursors such as [Ag2(R-Hpyrrld)(S-Hpyrrld)] and [Ag2(R-othf)(S-othf)]

  摘要 具有硬（O 供体）和软（P 供体）路易斯碱的新型金 (I) 络合物，[Au(R,S-Hpyrrld)(PPh3)] · CHCl3 1 (H2pyrrld = 2-pyrrolidone-5-羧酸)和 [Au(R,S-othf)(PPh3)] 2（Hothf = 5-oxo-2-四氢呋喃甲酸），是通过 [AuCl(PPh3)] 和 Ag-O 键合在 中的 AgCl 消除反应制备的前体，例如 [Ag2(R-Hpyrrld)(S-Hpyrrld)] 和 [Ag2(R-othf)(S-othf)]。1 的分子结构被确定为 2 坐标 AuOP 核心的离散单体。在制备 1 和 2 时，Ag-O 键合前体的使用至关重要。复合物 1 和 2 均显示出对革兰氏阳性菌和酵母菌的选择性抗菌活性。
• Syntheses, Structures, and Antimicrobial Activities of Light-Stable and Di- and Mononuclear Silver(I) Carboxylate Complexes Composed of Triphenylphosphine, and Chiral and Racemic Forms of 2-Pyrrolidone-5-carboxylic Acid (H₂pyrrld). A Variety of Ag–O Bonding Modes in the Silver(I) Complexes Constructed with Hard Oxygen and Soft Phosphorus Atoms
  作者：Ryusuke Noguchi、Akiyoshi Sugie、Yohei Okamoto、Akihiro Hara、Kenji Nomiya

  DOI：10.1246/bcsj.78.1953

  日期：2005.11

  Using light-stable dimeric silver(I) carboxylate precursors [Ag(Hpyrrld)]2}n formed with chiral and racemic forms of 2-pyrrolidone-5-carboxylic acid (H2pyrrld) ligand, six novel light-stable, triphenylphosphinesilver(I) complexes consisting of both a hard Lewis base (O atom) and a soft Lewis base (P atom) were prepared, i.e. [Ag2(R-Hpyrrld)2(H2O)(PPh3)2]·H2O (1), [Ag(R-Hpyrrld)(PPh3)2]2 (2), [Ag2(S-Hpyrrld)2(H2O)(PPh3)2]·H2O (3), [Ag(S-Hpyrrld)(PPh3)2]2 (4), [Ag(R,S-Hpyrrld)(PPh3)]2}n (5), and [Ag(R,S-Hpyrrld)(PPh3)2] (6). Their solid-state and solution structures were unequivocally characterized with elemental analysis, TG/DTA, FTIR, X-ray structure analysis, molecular weight measurements in EtOH with the vaporimetric method, solution (1H, 13C, and 31P) NMR, and solid-state 31P CPMAS NMR spectroscopy. Two sets of the enantiomeric complexes were isolated as (1 and 3) and (2 and 4). X-ray crystallography revealed that these complexes possessed different Ag–O bonding modes, depending on the number of PPh3 ligands and the chirality of the Hpyrrld− ligand. The complexes 1–6 behaved as a monomeric species in EtOH and CD2Cl2. The antimicrobial activites by the silver(I) complexes in the water–suspension system against selected bacteria, yeast, and molds, were significantly correlated with the number of coordinating PPh3 ligands per silver(I) atom in the complexes.

  of银(I)配合物在水悬浮液中对特定细菌、酵母菌和霉菌的抗菌活性与银(I)配合物的数量密切相关。
• Synthesis, reaction and structure of a highly light-stable silver(i) cluster with an Ag4S4N4 core having a tridentate 4N-morpholyl 2-acetylpyridine thiosemicarbazone ligand: Use of water-soluble silver(i) carboxylates as a silver(i) source
  作者：Kuniaki Onodera、Noriko Chikaraishi Kasuga、Tomomi Takashima、Akihiro Hara、Akifumi Amano、Hideyuki Murakami、Kenji Nomiya

  DOI：10.1039/b702427d

  日期：——

  tetrameric silver(I) cluster [Ag(mtsc)](4) was obtained from reactions of a tridentate (4)N-morpholyl 2-acetylpyridine thiosemicarbazone ligand (N'-[1-(2-pyridyl)ethylidene] morpholine-4-carbothiohydrazide, Hmtsc) and silver(I) sources containing Ag-O bonds (Ag(2)O, Ag(OAc), silver(I) 2-pyrrolidone-5-carboxylate (infinity)[Ag(Hpyrrld)](2)}, silver(I) 5-oxo-2-tetrahydrofurancarboxylate (infinity)[Ag(othf)](2)}

  新型中性四聚体银（I）簇[Ag（mtsc）]（4）从三齿（4）N-吗啉基2-乙酰吡啶硫代半碳a配体（N'-[1-（2-吡啶基）亚乙基]的反应中获得含有Ag-O键的Ag（2）O，Ag（OAc），2-吡咯烷酮5-羧酸盐（I）的吗啉-4-碳硫酰肼（Hmtsc）和银（I）来源[Ag（Hpyrrld ）]（2）}，5-氧代-2-四氢呋喃甲酸银（I）（无穷大）[Ag（othf）]（2）}和银（I）与樟脑酸（无穷大）[Ag（ca ）]}和（无穷大）[Ag（ca）（Hca）]}）。通过元素分析，TG / DTA，FTIR和固态单晶X射线分析对团簇进行表征。使用溶液分子量测量，ESI-MS和溶液（（1）H，（13）C和（31）P）NMR光谱研究了配合物的溶液性质。所获得的簇是具有三齿硫代半碳胺配体的光稳定的Ag（I）簇的新实例，并且是硫代半碳胺银（I）配合物的晶体结构的第二个报道。四聚体与大量过量的
• Solid channel structure and nanoscale drum-like Ag6 cluster constructed with pentafluorobenzenethiolate and triphenylphosphine ligands: The use of water-soluble silver(I) carboxylate as silver(I) source
  作者：Ryusuke Noguchi、Akihiro Hara、Akiyoshi Sugie、Kenji Nomiya

  DOI：10.1016/j.inoche.2005.10.003

  日期：2006.1

  A nanoscale drum-like hexanuclear silver(l) cluster [Ag(pfbt)(PPh3)](6) 1 (Hpfbt = pentafluorobenzenethiol), which showed the arrays of channels based on its self-assembly in the solid, was obtained by the 1: 1 molar-ratio reaction of the insoluble polymeric precursor(infinity)[Ag(pfbt)](2) and PPh3 in chloroform. Synthetic yield and purity of 1 were strongly dependent on the purity of 2. Compound 2 with higher purity was prepared in good yield using light-stable and water-soluble silver(l) carboxylate [Ag(Hpyrrld)](2) (H(2)pyrrld = 2-pyrrolidone-5-carboxylic acid) as the silver(I) source. (c) 2005 Elsevier B.V. All rights reserved.