RKKRRQRRR

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: RKKRRQRRR
• 英文别名: (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-oxopentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
• 化学式: C₅₃H₁₀₆N₃₀O₁₁
• 分子量: 1339.62
• InChiKey: KXLZCNROAUAFRT-IZROAPMXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -13.8
• 重原子数：
  94
• 可旋转键数：
  52
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  778
• 氢给体数：
  25
• 氢受体数：
  20

文献信息

• COMPOSITIONS AND METHODS FOR THE INTRACELLULAR DELIVERY OF ANTIBODIES
  申请人：The Trustees of Columbia University in the City of New York

  公开号：EP1575508A2

  公开（公告）日：2005-09-21
• [EN] COMPOSITIONS AND METHODS FOR THE INTRACELLULAR DELIVERY OF ANTIBODIES<br/>[FR] COMPOSITIONS ET PROCEDES POUR LA DELIVRANCE INTRACELLULAIRE D'ANTICORPS
  申请人：UNIV COLUMBIA

  公开号：WO2004030610A2

  公开（公告）日：2004-04-15

  This invention provides a composition of matter comprising an antibody and a peptide moiety, wherein the peptide moiety comprises an amino acid residue having a nitrogen-containing side chain and wherein the peptide is covalently bound to a carbohydrate moiety of the antibody. This invention also provides a pharmaceutical composition comprising the composition of matter and a pharmaceutically acceptable carrier. Finally, this invention provides methods and kits relating to the composition of matter.