Tris(hydroxymethyl)-(3-sulfopropyl)azanium

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: Tris(hydroxymethyl)-(3-sulfopropyl)azanium
• 化学式: C6H16NO6S+
• 分子量: 230.26
• InChiKey: WGERYXHFHWRZIH-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  -2.2
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  123
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• SUBSTITUTED BERBINES AND THEIR SYNTHESIS
  申请人：MALLINCKRODT LLC

  公开号：US20150099772A1

  公开（公告）日：2015-04-09

  The present invention provides substituted berbines, processes for the synthesis of substituted berbine compounds, as well as intermediates used in the synthesis of substituted berbine compounds. Also provided are methods for using the substituted berbines to inhibit cancer cell growth.

  本发明提供了替代苯并啉化合物，以及用于合成替代苯并啉化合物的工艺，以及合成替代苯并啉化合物所使用的中间体。还提供了使用替代苯并啉来抑制癌细胞生长的方法。
• Substituted Berbines and Processes for their Synthesis
  申请人：Wang Peter X.

  公开号：US20100056789A1

  公开（公告）日：2010-03-04

  The present invention provides processes for the synthesis of substituted berbine compounds. Also provided are intermediates used in the synthesis of substituted berbine compounds.

  本发明提供了合成取代苯并喹啉化合物的方法。还提供了在合成取代苯并喹啉化合物中使用的中间体。
• Arrangement and method for performing chromatography
  申请人：——

  公开号：US20020050471A1

  公开（公告）日：2002-05-02

  An arrangement for performing chromatography with a mobile phase and a chromatographic bed having a stationary phase is provided. The arrangement includes a support assembly configured to support the stationary phase. The support assembly has a sealed cavity configured so that when the support assembly is supporting the stationary phase a portion of the chromatographic bed and the stationary phase extends into the sealed cavity. The arrangement further includes a bladder having a void defined therein. The bladder is positioned within the sealed cavity. The arrangement also includes a fluid positioned within the void of the bladder so that the bladder is urged toward the stationary phase within the sealed cavity. The arrangement further includes an anode positioned in contact with the mobile phase. The arrangement also includes a cathode positioned in contact with the stationary phase, wherein creating an electrical potential between the anode and the cathode causes the mobile phase to be advanced through the chromatographic bed positioned within the sealed cavity. An associated method is also provided.

  提供了一种利用流动相和具有固定相的色谱床进行色谱分析的装置。该装置包括一个支撑组件，用于支撑固定相。支撑组件具有一个密封腔，当支撑组件支撑固定相时，色谱床和固定相的一部分延伸到密封腔中。该装置还包括一个囊体，囊体上有一个空隙。膀胱位于密封腔内。该装置还包括一个位于膀胱空隙内的流体，使膀胱被推向密封腔内的固定相。该装置还包括一个与流动相接触的阳极。该装置还包括一个与固定相接触的阴极，在阳极和阴极之间产生电势，使流动相通过密封腔内的色谱床。还提供了一种相关的方法。
• SUBSTITUTED BERBINES AND PROCESSES FOR THEIR SYNTHESIS
  申请人：Mallinckrodt LLC

  公开号：EP2331508B1

  公开（公告）日：2014-11-12
• METHOD AND SYSTEM FOR SEPARATING ANALYTES
  申请人：Nurok David

  公开号：US20100059442A1

  公开（公告）日：2010-03-11

  A method and device for performing chromatography includes placing a monolithic polymer layer in contact with a liquid mobile phase. The monolithic polymer layer may be neutral, positively charged, or negatively charged. A first electrode and second electrode are coupled to the monolithic polymer layer. An electrical potential is created between the first electrode and the second electrode. In some embodiments, the monolithic polymer layer may be placed in a sealed chamber, which may have a pressure greater than atmospheric pressure. Additionally, in some embodiments, the mobile phase is advanced through the monolithic polymer layer via one of a number of forced flow techniques.