2,4,6,8,10,12,14-hexadecaheptaenol | 1060652-66-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2,4,6,8,10,12,14-hexadecaheptaenol
• 英文别名: (2E,4E,6E,8E,10E,12E,14E)-hexadeca-2,4,6,8,10,12,14-heptaen-1-ol
• CAS: 1060652-66-5
• 化学式: C₁₆H₂₀O
• 分子量: 228.334
• InChiKey: HCUAZCJTQWKJFQ-FDVVZRHWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  (2E,4E,6E,8E,10E,12E,14E)-Hexadecaheptaenal 在 sodium tetrahydroborate 作用下， 以 乙醇 为溶剂， 反应 5.0h， 以40%的产率得到2,4,6,8,10,12,14-hexadecaheptaenol
  参考文献：
  名称：

  醋酸醋杆菌将多共轭化合物直接转化为其相应的羧酸

  摘要：

  使用醋酸醋杆菌（Acetobacter aceti）将多共轭醛或醇转化为相应的酸。将分析结果与使用霍纳-维蒂希反应化学获得的酸进行了比较。

  DOI：

  10.1016/j.tet.2008.07.011

文献信息

• [EN] POLYUNSATURATED LINEAR ALDEHYDES AND THEIR DERIVATIVES WITH ANTI-RADICAL AND ANTI-TUMORAL ACTIVITY<br/>[FR] ALDEHYDES LINEAIRES POLYINSATURES ET LEURS DERIVES A ACTIVITE ANTI-RADICALAIRE ET ANTI-TUMORALE
  申请人：UNIV DEGLI STUDI MILANO

  公开号：WO2003095403A1

  公开（公告）日：2003-11-20

  The invention relates to polyunsaturated linear aldehydes and derivatives thereof which can be extracted from the feathers or tissues of parrots of prepared synthetically with antioxidant, antitumoral and anti-inflammatory activity, and which are useful in the prevention and treatment of cardiovascular, inflammatory, atherosclerotic, proliferative cell and tumour damage and the prevention of alterations caused by ageing.

  本发明涉及从鹦鹉的羽毛或组织中提取或通过合成制备的多不饱和线性醛及其衍生物，具有抗氧化、抗肿瘤和抗炎活性，并可用于预防和治疗心血管、炎症、动脉粥样硬化、增生细胞和肿瘤损伤以及预防衰老引起的变化。
• Polyunsaturated linear aldehydes and their derivatives with anti-radical and anti-tumoral activity
  申请人：Stradi Riccardo

  公开号：US20050175555A1

  公开（公告）日：2005-08-11

  The invention relates to polyunsaturated linear aldehydes and derivatives thereof which can be extracted from the feathers or tissues of parrots of prepared synthetically with antioxidant, antitumoral and anti-inflammatory activity, and which are useful in the prevention and treatment of cardiovascular, inflammatory, atherosclerotic, proliferative cell and tumour damage and the prevention of alterations caused by ageing.

  本发明涉及从鹦鹉的羽毛或组织中提取或合成的多不饱和线性醛及其衍生物，具有抗氧化、抗肿瘤和抗炎活性，可用于预防和治疗心血管、炎症性、动脉粥样硬化、增殖细胞和肿瘤损伤以及预防衰老引起的变化。
• POLYUNSATURATED LINEAR ALDEHYDES AND THEIR DERIVATIVES WITH ANTI-RADICAL AND ANTI-TUMORAL ACTIVITY
  申请人：UNIVERSITA'DEGLI STUDI DI MILANO

  公开号：EP1501774A1

  公开（公告）日：2005-02-02
• POLYUNSATURATED LINEAR ALDEHYDES AND THEIR DERIVATIVES WITH ANTI-RADICAL ACTIVITY
  申请人：Giuliani S.p.A.

  公开号：EP1501774B1

  公开（公告）日：2009-08-12
• Direct conversion of polyconjugated compounds into their corresponding carboxylic acids by Acetobacter aceti
  作者：Elena Pini、Vittorio Bertacche、Francesco Molinari、Diego Romano、Raffaella Gandolfi

  DOI：10.1016/j.tet.2008.07.011

  日期：2008.9

  The conversion of polyconjugated aldehydes or alcohols into their corresponding acids was carried out using Acetobacter aceti. The analytical results were compared with those of the acids chemically obtained using a Horner–Wittig reaction.

  使用醋酸醋杆菌（Acetobacter aceti）将多共轭醛或醇转化为相应的酸。将分析结果与使用霍纳-维蒂希反应化学获得的酸进行了比较。