2-[4-[2-[(Z)-octadec-9-enoyl]oxyethyl]piperazin-1-yl]ethanesulfonic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-[4-[2-[(Z)-octadec-9-enoyl]oxyethyl]piperazin-1-yl]ethanesulfonic acid
• 化学式: C₂₆H₅₀N₂O₅S
• 分子量: 502.8
• InChiKey: DURKKQBYWSQJBF-KTKRTIGZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  34
• 可旋转键数：
  22
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  95.5
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• Composition and method for treating acne including anti-inflammatory Hepes Oleate
  申请人：Watson M. Dana

  公开号：US20060019935A1

  公开（公告）日：2006-01-26

  The present invention is directed toward a topical composition for the treatment of acne comprising water, an anti-acne agent such as benzoyl peroxide, thickening agent, emulsifiers, stabilizers, and a natural esterified anti-inflammatory (Hepes Oleate). This combined therapy is more effective than either active ingredient alone and is particularly effective for those who do not respond well to benzoyl peroxide alone.

  本发明涉及一种治疗痤疮的外用组合物，该组合物由水、抗痤疮剂（如过氧化苯甲酰）、增稠剂、乳化剂、稳定剂和天然酯化消炎剂（油酸庚酯）组成。这种综合疗法比单独使用其中一种活性成分更有效，对于那些对单独使用过氧化苯甲酰反应不佳的人尤其有效。
• ZWITTERIONIC FATTY ACID COMPOUNDS FOR ANTI-INFLAMATION
  申请人：Pugliese, Peter T.

  公开号：EP1033913A1

  公开（公告）日：2000-09-13
• Composition and method for managing redness of skin associated with dermatological condition
  申请人：Watson M. Dana

  公开号：US20070248555A1

  公开（公告）日：2007-10-25

  The present invention is directed towards a topical composition for managing redness of skin associated with a dermatological condition, comprising water, gelled ethyl alcohol (an anti-bacterial), anti-oxidants, thickening agents, emulsifiers, stabilizers, and a natural esterified anti-inflammatory (Hepes). This combined therapy is more effective than anti-bacterial agents alone and is particularly effective for those who do not respond well to the solutions containing only anti-bacterial agents.
• US6114337A
  申请人：——

  公开号：US6114337A

  公开（公告）日：2000-09-05
• US6448251B1
  申请人：——

  公开号：US6448251B1

  公开（公告）日：2002-09-10