(R)-(-)-1,3-壬烷二醇 - CAS号 23433-07-0

物化性质

熔点：

44.4°C (estimate)
沸点：

271-272 °C(lit.)
密度：

>0.929 g/mL at 25 °C(lit.)
闪点：

>230 °F

计算性质

辛醇/水分配系数(LogP)：

2.2
重原子数：

11
可旋转键数：

7
环数：

0.0
sp3杂化的碳原子比例：

1.0
拓扑面积：

40.5
氢给体数：

2
氢受体数：

2

安全信息

海关编码：

2905399090

SDS

SDS：66129f24136e7ab2026ccf5f85c4ae4a

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Name:	(R)-(-)-1,3-Nonanediol Material Safety Data Sheet
Synonym:	None Known.
CAS:	23433-07-0

Section 1 - Chemical Product MSDS Name: (R)-(-)-1,3-Nonanediol Material Safety Data Sheet
Synonym: None Known.

SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
23433-07-0	(R)-(-)-1,3-Nonanediol		245-660-2

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

SECTION 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW The toxicological properties of this material have not been fully investigated. Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

SECTION 4 - FIRST AID MEASURES
Eyes:
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

SECTION 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

SECTION 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.

SECTION 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 23433-07-0: Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: colorless
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 122 - 124 deg C @ 1.5 mmHg
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density: 0.9198
Molecular Formula: C9H20O2
Molecular Weight: 160.26

SECTION 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
None reported.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

SECTION 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 23433-07-0: RA6475650
LD50/LC50:
CAS# 23433-07-0: Oral, rat: LD50 = >20 gm/kg.
Carcinogenicity:
(R)-(-)-1,3-Nonanediol - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

SECTION 12 - ECOLOGICAL INFORMATION

SECTION 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations.

SECTION 14 - TRANSPORT INFORMATION IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR Not regulated as a hazardous material.

SECTION 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 23433-07-0: No information available. Canada CAS# 23433-07-0 is listed on Canada's NDSL List. CAS# 23433-07-0 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 23433-07-0 is listed on the TSCA inventory.

SECTION 16 - ADDITIONAL INFORMATION
MSDS Creation Date: 1/16/2002 Revision #1 Date: 9/19/2002 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the company has been advised of the possibility of such damages.

SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

作为反应物：

描述：

(R)-(-)-1,3-壬烷二醇、硼酸生成 4-Hexyl-2-hydroxy-1,3,2-dioxaborinane

参考文献：

名称：

KAMARS A. EH.; SHVARTS E. M., IZV. AN LATVSSR. CEP. XIM.,(1986) N 6, 700-707

摘要：

DOI：
作为产物：

描述：

2-羟基油酸生成 (R)-(-)-1,3-壬烷二醇

参考文献：

名称：

ω-羟基脂肪酸及其酯的改进制备

摘要：

通过硼氢化钠或通过氢化作用对脂肪酸的臭氧化物和它们的酯进行还原裂解，分别以高产率产生 ω-羟基脂肪酸和 ω-羟基脂肪酯。

DOI：

10.1139/v60-266

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文献信息

POLYUNSATURATED FATTY ACID AND DIOL ESTER AS AN ANTI-ACNE AGENT

申请人：Redoules Daniel

公开号：US20110230557A1

公开（公告）日：2011-09-22

The present invention relates to compounds of the following formula (I): where n is an integer between 1 and 15, m is 0, 1, 2 or 3, and R is the hydrocarbon chain of a polyunsaturated fatty acid selected from among omega 3 and omega 6, as well as to pharmaceutical or cosmetic compositions containing same, to a method for preparing and using same, in particular for treating acne and seborrhoeic dermatitis.

本发明涉及以下式（I）的化合物：其中n是1到15之间的整数，m是0、1、2或3，R是从ω-3和ω-6中选择的多不饱和脂肪酸的烃链，以及含有相同化合物的药用或化妆品组合物，以及制备和使用相同的方法，特别用于治疗痤疮和脂溢性皮炎。
BENZAZEPIN-2(1H)-ONE DERIVATIVES

申请人：Boyle Jessica

公开号：US20080103130A1

公开（公告）日：2008-05-01

Compounds of formula (I) and pharmaceutically acceptable salts thereof are agonists at the beta-2 adrenoceptor. They are useful as feed additives for livestock animals.

式(I)的化合物及其药用可接受的盐是β-2肾上腺素受体的激动剂。它们可用作家畜动物的饲料添加剂。
ANTIPARASITIC AGENTS

申请人：Comlay Stuart Nicholas

公开号：US20080194694A1

公开（公告）日：2008-08-14

The present invention relates to compounds of the formula (I) or a tautomer or prodrug thereof, or a pharmaceutically acceptable salt of said compound, tautomer or prodrug, wherein: R 1 , R 2 , R 3 , R 4 and R 5 are each independently selected from H, halo, CN, CF 3 and CONH 2 ; compositions containing such compounds and the uses of such compounds as antiparasitic agents.

本发明涉及具有以下结构式（I）的化合物，或其互变异构体或前药，或该化合物、互变异构体或前药的药用盐，其中：R1、R2、R3、R4和R5分别独立选择自H、卤、CN、CF3和CONH2；含有这种化合物的组合物以及这种化合物作为抗寄生虫剂的用途。
1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF

申请人：REG Life Sciences LLC

公开号：US20180072645A1

公开（公告）日：2018-03-15

The disclosure relates to the field of specialty chemicals. In particular, the disclosure provides novel 1,3-fatty-diol compounds and derivatives thereof which are useful e.g., in the production of personal care products, surfactants, detergents, polymers, paints, coatings, and as emulsifiers, emollients, and thickeners in cosmetics and foods, as industrial solvents and plasticizers, etc.

本公开涉及专业化学领域。具体而言，本公开提供了新颖的1,3-脂肪二醇化合物及其衍生物，可用于个人护理产品、表面活性剂、洗涤剂、聚合物、涂料、涂层的生产，以及作为化妆品和食品中的乳化剂、润肤剂和增稠剂，工业溶剂和增塑剂等。
Active-releasing cyclic siloxanes

申请人：Perry J. Robert

公开号：US20050136021A1

公开（公告）日：2005-06-23

Cyclic siloxanes that contain releasable active ingredients are described. The active ingredient can be an alcohol or enolizable carbonyl-containing compound such as a ketone, aldehyde, or ester. The product siloxanes are useful in a variety of personal and household care products where slow or controlled release of active ingredient is desired. A preferred embodiment utilizes substituents that when released as active ingredients are fragrant.

本文描述了含有可释放活性成分的环状硅氧烷。活性成分可以是醇或可烯化羰基含有化合物，如酮，醛或酯。该产品硅氧烷在需要缓慢或受控释放活性成分的各种个人和家庭护理产品中非常有用。一种首选实施方案利用了当作为活性成分释放时具有香味的取代基。

(R)-(-)-1,3-壬烷二醇 | 23433-07-0

分子结构分类

物化性质

计算性质

安全信息

SDS

反应信息

文献信息

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