N(omega)-nitroso-L-arginine

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N(omega)-nitroso-L-arginine
• 英文别名: (2S)-2-amino-5-[[amino-(2-oxohydrazinyl)methylidene]amino]pentanoic acid
• 化学式: C₆H₁₃N₅O₃
• 分子量: 203.2
• InChiKey: DFSJTMFCAJNYBY-BYPYZUCNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.5
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  143
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• Peptides for the treatment of malignant proliferative diseases
  申请人：Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

  公开号：US10570174B2

  公开（公告）日：2020-02-25

  Synthetic peptides containing chemical modifications having anti-tumor properties are provided. Further provided are pharmaceutical compositions including the peptides and use thereof for treating proliferative and neoplastic diseases such as cancer.

  提供了含有具有抗肿瘤特性的化学修饰的合成肽。此外，还提供了包括这些肽的药物组合物及其在治疗增殖性和肿瘤性疾病（如癌症）中的应用。
• PEPTIDES FOR THE TREATMENT OF MALIGNANT PROLIFERATIVE DISEASES
  申请人：Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

  公开号：US20180037607A1

  公开（公告）日：2018-02-08

  Synthetic peptides containing chemical modifications having anti-tumor properties are provided. Further provided are pharmaceutical compositions including the peptides and use thereof for treating proliferative and neoplastic diseases such as cancer.
• METHODS AND COMPOSITIONS FOR INCREASING TOLERANCE TO ABIOTIC STRESS IN PLANTS
  申请人：CROP MICROCLIMATE MANAGEMENT INC.

  公开号：US20210037717A1

  公开（公告）日：2021-02-11

  The present invention relates to compositions and methods for increasing tolerance to abiotic stress and/or for reducing the consequence of abiotic stress in a plant and/or part thereof. In some aspects, the method comprises contacting a plant and/or part thereof with a first composition comprising one or more of aminoguanidine, L-nitroarginine, L-nitroarginine methyl ester, 2,2′-bipyridine, 4-methylpyrazole, 8-hydroxyquiniline, caprylic acid, pyrazole, naringenin, kaempferol, quercetin, dodecanoic acid, and/or undecanoic acid, and/or a salt thereof; and a second composition comprising at least one dicarboxylic acid and/or a salt thereof.