Acetic acid;2-amino-3-hydroxypropanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Acetic acid;2-amino-3-hydroxypropanoic acid
• 化学式: C7H15NO7
• 分子量: 225.2
• InChiKey: WPMHLIFQOICLTE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.43
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  158
• 氢给体数：
  5
• 氢受体数：
  8

文献信息

• [EN] NEW SALTS, CRYSTALS, COMPLEXES, AND DERIVATIVES OF THREONINE DIACETIC ACID, A PROCESS TO PREPARE THREONINE DIACETIC ACID, AND THE USE THEREOF<br/>[FR] NOUVEAUX SELS, CRISTAUX, COMPLEXES ET DÉRIVÉS D'ACIDE DIACÉTIQUE DE THRÉONINE, PROCÉDÉ DE PRÉPARATION DUDIT ACIDE ET UTILISATION ASSOCIÉE
  申请人：AKZO NOBEL CHEMICALS INT BV

  公开号：WO2015007630A1

  公开（公告）日：2015-01-22

  The present invention relates to new salts, complexes, crystals, solutions, dispersions, and slurries of threonine-N,N-diacetic acid or derivatives thereof, to formulations containing those, to processes to prepare those, and to the use thereof.

  本发明涉及苏氨酸-N，N-二乙酸或其衍生物的新盐、配合物、晶体、溶液、分散液和浆料，以及含有它们的配方、制备这些物质的过程以及它们的用途。
• New Salts, Crystals, Complexes, and Derivatives of Threonine Diacetic Acid, a Process to Prepare threonine Diacetic Acid, and the Use Thereof
  申请人：AKZO NOBEL CHEMICALS INTERNATIONAL B.V.

  公开号：US20160159730A1

  公开（公告）日：2016-06-09

  The present invention relates to new salts, complexes, crystals, solutions, dispersions, and slurries of threonine-N,N-diacetic acid or derivatives thereof, to formulations containing those, to processes to prepare those, and to the use thereof.

  本发明涉及苏氨酸-N，N-二乙酸或其衍生物的新盐，配合物，晶体，溶液，分散液和泥浆，含有这些物质的配方，制备这些物质的过程以及其用途。
• PROCESSES FOR PRODUCING AMINO ACID HAVING SECONDARY OR TERTIARY AMINO GROUP AND THREE OR MORE CARBOXYL GROUPS AND ITS SALT
  申请人：Showa Denko Kabushiki Kaisha

  公开号：EP1004571A1

  公开（公告）日：2000-05-31

  An amino acid having a secondary or tertiary amino group and three or more carboxyl groups (AADA) or its salt with an equivalent or less of an alkali metal is produced by reducing, through electrodialysis, alkali metal ions from an aqueous solution of the alkali metal salt of an amino acid having a secondary or tertiary amino group and three or more carboxyl groups. By this configuration, an AADA salt can be produced in a much higher yield than conventional equivalents without requiring a regeneration operation of a resin as in the use of an ion exchange resin or without requiring crystallization-separation of crystals of the AADA salt as in the addition of an organic solvent. A salt of an amino acid having a secondary or tertiary amino group and three or more carboxyl groups is produced by reacting an amino acid having a secondary or tertiary amino group and three or more carboxyl groups with any of metal oxides, metal hydroxides, metal carbonates, metal hydrogencarbonates, ammonium hydroxide, ammonium carbonate, ammonium hydrogencarbonate or organic amine compounds. By this configuration, a metal salt, ammonium salt or organic amine salt of an AADA can be produced with efficiency without the formation of by-products.

  通过电渗析，从具有仲或叔氨基和三个或三个以上羧基的氨基酸的碱金属盐的水溶液中还原碱金属离子，制得具有仲或叔氨基和三个或三个以上羧基的氨基酸（AADA）或其等量或等量以下的碱金属盐。通过这种结构，无需像使用离子交换树脂那样对树脂进行再生操作，也无需像添加有机溶剂那样对 AADA 盐的晶体进行结晶分离，就能生产出比传统等价物产量高得多的 AADA 盐。 具有二级或三级氨基和三个或三个以上羧基的氨基酸盐是通过具有二级或三级氨基和三个或三个以上羧基的氨基酸与金属氧化物、金属氢氧化物、金属碳酸盐、金属碳酸氢盐、氢氧化铵、碳酸铵、碳酸氢铵或有机胺化合物中的任何一种反应制得的。通过这种配置，可以高效地生产出 AADA 的金属盐、铵盐或有机胺盐，而不会形成副产品。
• DISINFECTANT COMPOSITION AND DISINFECTING METHOD
  申请人：Lion Corporation

  公开号：EP2476314A1

  公开（公告）日：2012-07-18

  The present invention relates to a disinfectant composition containing the following components (A) to (D): component (A): a zinc compound, component (B): a chelate compound represented by the following general formula (b1) or (b2), component (C): hydrogen peroxide or a peroxide that releases hydrogen peroxide in water, and component (D): an organic peroxy acid precursor that generates an organic peroxy acid by reacting with the component (C). According to the present invention, a disinfectant composition and a disinfecting method can be provided that enable the effective elimination of gram negative bacteria adhered to textile products, and particularly cotton products.

  本发明涉及一种消毒剂组合物，其中含有以下组分（A）至（D）：组分（A）：锌化合物；组分（B）：由以下通式（b1）或（b2）表示的螯合物；组分（C）：过氧化氢或在水中释放过氧化氢的过氧化物；组分（D）：有机过氧酸前体，通过与组分（C）反应生成有机过氧酸。根据本发明，可以提供一种消毒剂组合物和消毒方法，能够有效消除纺织品，特别是棉制品上附着的革兰氏阴性细菌。
• MEDICINAL COMPOSITION FOR PROMOTING SYNTHESIS OF PROTOPORPHYRIN IX
  申请人：SBI Pharmaceuticals Co., Ltd.

  公开号：EP3011972A1

  公开（公告）日：2016-04-27

  The object of the present invention is to elucidate the resistance mechanism in infections that show resistance to ALA-PDT that uses a single ALA, and to provide a novel treatment method against these infections. The present invention provides a pharmaceutical composition for promoting protoporphyrin IX production in ALA-PDT for treating infection, characterized in that it comprises a substance that promotes the conversion from coproporphyrinogen III to protoporphyrin IX.

  本发明的目的是阐明对使用单一ALA的ALA-PDT显示抗性的感染的抗性机理，并提供一种针对这些感染的新型治疗方法。本发明提供了一种在治疗感染的 ALA-PDT 中促进原卟啉 IX 生成的药物组合物，其特征在于它包含一种促进共卟啉原 III 向原卟啉 IX 转化的物质。