2''-Hydroxynicotianamine

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2''-Hydroxynicotianamine
• 英文别名: (2S)-1-[(3S)-3-[[(3S)-3-amino-3-carboxy-2-hydroxypropyl]amino]-3-carboxypropyl]azetidine-2-carboxylic acid
• 化学式: C₁₂H₂₁N₃O₇
• 分子量: 319.31
• InChiKey: AEFGUQJJQWSYJR-QKDHONSWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -9.2
• 重原子数：
  22
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  173
• 氢给体数：
  6
• 氢受体数：
  10

文献信息

• 2"-Hydroxynicotianamine, process for producing the same and angiotensin converting enzyme inhibitor, hypotensive drug and health food
  申请人：Aoyagi Yasuo

  公开号：US20070043018A1

  公开（公告）日：2007-02-22

  The invention provides 2″-hydroxynicotianamine; a method for producing 2″-hydroxynicotianamine comprising the step of obtaining an extract solution from a buckwheat sample followed by obtaining a fraction having an inhibitory activity for the angiotensin-converting enzyme by ion-exchange chromatography using an anion exchange resin; novel substances having an ACE inhibitory activity by preparing an inhibitor for the angiotensin-converting enzyme, a vasodepressor agent and a health food each containing 2″-hydroxynicotianamine; methods for producing the novel substances; an inhibitor for the angiotensin-converting enzyme and a vasodepressor agent having the novel substance as an effective ingredient; and a health food containing the novel substance.