H-Lys-Glu-Asp-Pro-OH

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: H-Lys-Glu-Asp-Pro-OH
• 英文别名: (2S)-1-[(2S)-3-carboxy-2-[[(2S)-4-carboxy-2-[[(2S)-2,6-diaminohexanoyl]amino]butanoyl]amino]propanoyl]pyrrolidine-2-carboxylic acid
• 化学式: C₂₀H₃₃N₅O₉
• 分子量: 487.5
• InChiKey: WUCUNGRTSFLCLI-XUXIUFHCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -9
• 重原子数：
  34
• 可旋转键数：
  15
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  242
• 氢给体数：
  7
• 氢受体数：
  11

文献信息

• TETRAPEPTIDE REGULATING PROSTATE FUNCTIONS AND ITS COMPOSITIONS AND METHODS
  申请人：Sankt-Peterburgskaya Obschestvennaya Organizatsia "Sankt-Peterburgskiy Institut Biroregulyatsii I Gerontologii Szo Ramn"

  公开号：EP1353939A2

  公开（公告）日：2003-10-22
• TETRAPEPTIDE REGULATING PROSTATE FUNCTIONS AND ITS COMPOSITIONS AND USES
  申请人：Sankt-Peterburgskaya Obschestvennaya Organizatsia "Sankt-Peterburgskiy Institut Bioregulyatsii I Gerontologii Szo Ramn"

  公开号：EP1353939B1

  公开（公告）日：2004-08-25
• [EN] TETRAPEPTIDE REGULATING PROSTATE FUNCTIONS AND ITS COMPOSITIONS AND METHODS<br/>[FR] TETRAPEPTIDE REGULANT LES FONCTIONS DE LA PROSTATE, SUBSTANCE PHARMACOLOGIQUE A BASE DE CE TETRAPEPTIDE ET PROCEDE D'APPLICATION CORRESPONDANT
  申请人：SANKT PETERBURGSKAYA OBSCHESTV

  公开号：WO2002066497A2

  公开（公告）日：2002-08-29

  The invention refers to the field of medicine and can be applied for regulation prostate functions. Biologically active tetrapeptide of the general formula Lys-Glu-Asp-Pro, a pharmaceutical preparation capable of regulation the prostate functions and containing an effective amount of Lys-Glu-Asp-Pro tetrapeptide or one of its salts and a pharmaceutically admissible carrier intended for the parenteral administration. In addition a method of regulation the prostate functions embraces administration of the pharmaceuutical preparation in the dose of 0.01-100 µg/kg of the bo dy weight at least once a day during a period required for attaining a therapeutic effect.