ZINC;2-amino-3-sulfanylpropanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: ZINC;2-amino-3-sulfanylpropanoate
• 化学式: C6H12N2O4S2Zn
• 分子量: 305.7
• InChiKey: FHIDHDJKGHORIB-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -4.02
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  134
• 氢给体数：
  4
• 氢受体数：
  8

文献信息

• Multifunction "Crown Complexes" from Amino Acids and Peptides for Skin and Hair Restoration
  申请人：Gupta K Shyam

  公开号：US20070099886A1

  公开（公告）日：2007-05-03

  This invention relates to Schiff's bases derived from amino acids and hydroxyaryl alkyl ketones, or a plant extract containing the same, having general chemical structure in FIG. 1 for topical application. This invention also relates to certain metal complex of said Schiff's bases, which have a crown-like appearance in their three-dimensional chemical structure, as in FIG. 2 . The Schiff's bases and their metal complexes of the present invention are useful for the modulation of metal-activated enzymes and metalloenzymes, such as Phenylalanine Hydroxylase, Tyrosine Transaminase, Phenylalanine Transaminase, Tyrosinase, various MMP (Matrix metalloproteases), Superoxide dismutase, 5-Alpha Reductase, and citrate lyase. These are further suitable for multifunctional topical methods for skin whitening, skin wrinkles reduction, skin antiaging, collagen synthesis, acne control, hair loss prevention, hair graying control, and facial oil control.

  本发明涉及从氨基酸和羟基芳基烷基酮衍生的席夫碱，或含有该类化合物的植物提取物，其具有图1中的一般化学结构，用于局部应用。本发明还涉及所述席夫碱的某些金属配合物，其在三维化学结构中呈冠状外观，如图2所示。本发明的席夫碱及其金属配合物对于调节金属活化酶和金属酶，例如苯丙氨酸羟化酶、酪氨酸转氨酶、苯丙氨酸转氨酶、酪氨酸酶、各种基质金属蛋白酶、超氧化物歧化酶、5α-还原酶和柠檬酸裂解酶具有用途。此外，它们还适用于多功能局部方法，如美白肌肤、减少皮肤皱纹、抗衰老、胶原蛋白合成、控制痤疮、预防脱发、控制白发和面部油脂控制。
• Hair Loss Prevention by Natural Amino Acid and Peptide Complexes
  申请人：GUPTA SHYAM K

  公开号：US20090253668A1

  公开（公告）日：2009-10-08

  This invention relates to certain skin and hair care agents of formula (I), derived from natural amino acids and peptides. These agents provide multi-functional treatment of enzyme-related skin, hair and scalp problems, for example, hair aging including premature hair loss and hair graying; male pattern baldness; hair loss from dandruff; alopecia; split ends, acne, darkened skin, dark circles around eyes, stretch marks, wrinkles and fine lines, loss of collagen, loss of skin pliability and combinations thereof:

  本发明涉及公式（I）的某些皮肤和头发护理剂，这些护理剂源自天然氨基酸和肽。这些护理剂提供多功能的酶相关皮肤、头发和头皮问题的治疗，例如，头发老化，包括过早脱发和白发；男性型脱发；头皮屑引起的脱发；脱发斑秃；分叉，痤疮，皮肤变黑，眼周黑眼圈，妊娠纹，皱纹和细纹，胶原蛋白流失，皮肤柔韧性流失和它们的组合：
• Skin and Hair Restoration by Natural Amino Acid and Peptide Crown Complexes
  申请人：GUPTA SHYAM K.

  公开号：US20080287536A1

  公开（公告）日：2008-11-20

  This invention relates to certain skin and hair care agents of formula (I), derived from natural amino acids and peptides. These agents provide multi-functional treatment of enzyme-related topical problems, for example, darkened skin including age spots, circles around eyes and stretch marks; skin conditions related to acne including excess facial oil and facial pore size; premature hair aging including hair loss and graying; inflammation including intra-cellular and extra-cellular inflammation; skin aging including wrinkles and fine lines; loss of collagen including thinning skin and loss of skin pliability; malfunction of tyrosinase group of enzymes; malfunction of matrix metalloprotease group of enzymes; and combinations thereof: Wherein, R, R′, and R″=any substituent(s); and M=H, Li, Na, K, Ca, Mg, Zn, Mn, Cu, Fe, Co, Mo, V, Cr, Ammonium, Alkyl ammonium, and Nitrogen Heterocyclic ammonium.

  本发明涉及一种公式（I）的天然氨基酸和肽衍生的某些皮肤和头发护理剂。这些剂提供了多功能的酶相关局部问题治疗，例如黑色皮肤，包括老年斑，眼周圆圈和妊娠纹; 与痤疮相关的皮肤状况，包括过多的面部油脂和面部毛孔大小; 早期头发老化，包括脱发和变白; 炎症，包括细胞内和细胞外炎症; 皮肤老化，包括皱纹和细纹; 胶原蛋白丢失，包括皮肤变薄和失去弹性; 酪氨酸酶类酶的功能障碍; 基质金属蛋白酶酶类的功能障碍; 以及它们的组合：其中，R，R'和R'' = 任何取代基; M = H，Li，Na，K，Ca，Mg，Zn，Mn，Cu，Fe，Co，Mo，V，Cr，铵，烷基铵和氮杂环铵。
• Zinccysteinat zur Behandlung von Entzündungen oder Allergien der Atemwege
  申请人：Geske, Gundula

  公开号：EP1832278A1

  公开（公告）日：2007-09-12

  Die vorliegende Erfindung betrifft die Verwendung von Zinkcysteinat zur Herstellung einer pharmazeutischen Zusammensetzung zur Behandlung von Entzündungen oder Allergien der Atemwege, sowie ein Medizinprodukt umfassend Zinkcysteinat als Wirkstoff, welches als Spray formuliert ist.

  本发明涉及半胱氨酸锌用于制备治疗呼吸道炎症或过敏的药物组合物，还涉及一种由半胱氨酸锌作为活性成分配制成喷雾剂的医疗器械。
• Antiviral disinfectants and their applications
  申请人：Gojo Industries, Inc.

  公开号：EP2332583A1

  公开（公告）日：2011-06-15

  This invention provides a method of inactivating non-enveloped virus particles. The method includes the step of contacting the virus with a virucidally-enhanced alcoholic composition that includes an alcohol, and an enhancer selected from the group consisting of cationic oligomers and polymers, proton donors, chaotropic agents, and mixtures thereof.

  本发明提供了一种灭活无包膜病毒颗粒的方法。该方法包括将病毒与病毒增强酒精组合物接触的步骤，该组合物包括酒精和一种增强剂，增强剂选自阳离子低聚物和聚合物、质子供体、混沌剂及其混合物组成的组。