6-Octadecadienoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 6-Octadecadienoic acid
• 英文别名: (4E,6E)-octadeca-4,6-dienoic acid
• 化学式: C₁₈H₃₂O₂
• 分子量: 280.4
• InChiKey: PJSQIDIRJGWHOB-SQIWNDBBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  20
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.72
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Compositions comprising reverse isomers of conjugated linoleic acid
  申请人：Saebo Asgeir

  公开号：US20050215641A1

  公开（公告）日：2005-09-29

  The present invention relates to the field of human and animal nutrition, and in particular to certain novel compositions of conjugated linoleic acids (CLA). In particular, the present invention relates to CLA compositions comprising the c10,t12, c10,c12, t9,c11 and c9,c11 isomers of conjugated linoleic acid.

  本发明涉及人类和动物营养领域，特别是某些新颖的共轭亚油酸（CLA）组合物。具体而言，本发明涉及包含共轭亚油酸的c10,t12、c10,c12、t9,c11和c9,c11异构体的CLA组合物。
• [EN] PRODUCTION AND PURIFICATION OF ESTERS OF CONJUGATED LINOLEIC ACIDS<br/>[FR] FABRICATION ET PURIFICATION D'ESTERS D'ACIDES LINOLEIQUES CONJUGUES
  申请人：STEPAN CO

  公开号：WO2005067888A1

  公开（公告）日：2005-07-28

  A process to refine esters of conjugated linoleic acids via distillation in a single or multi-pass distillation operation is provided. Thermal rearrangement of conjugated linoleic acid components during distillation is prevented or reduced by the use of a low residence time and/or reduced pressure distillation apparatus. A process to produce refined esters of conjugated linoleic acids is also provided. The process transesterifies a linoleic acid-containing oil to generate an alkyl ester composition which further undergoes isomerization at a temperatures typically between about 90-140 °C to form an ester stream containing conjugated linoleic acid esters, which is then distilled to obtain the refined esters of conjugated linoleic acids. The transesterification and isomerization steps can be performed in one reaction vessel without an intervening distillation step. The transesterification and isomerization steps can occur concurrently in a continuous reaction system using a dual reaction zone apparatus. Refined ester compositions produced by the processes and enriched in desirable conjugated linoleic acid isomers are also contemplated.

  提供了一种通过单通或多通蒸馏操作来精制共轭亚油酸酯的过程。通过使用低停留时间和/或降低压力的蒸馏设备，可以防止或减少共轭亚油酸组分在蒸馏过程中的热重排。还提供了一种生产精制共轭亚油酸酯的过程。该过程通过酯交换将含亚油酸的油转化为生成烷基酯组合物，然后在通常在约90-140°C之间的温度下进行异构化，形成含有共轭亚油酸酯的酯流，然后对其进行蒸馏以获得精制的共轭亚油酸酯。酯交换和异构化步骤可以在一个反应容器中进行，而无需中间的蒸馏步骤。酯交换和异构化步骤可以在连续反应系统中同时进行，使用双反应区设备。此外，还考虑了由这些过程产生的富含理想共轭亚油酸异构体的精制酯组合物。
• Process for preparing conjugated linoleic acid
  申请人：Rubin David

  公开号：US20060178521A1

  公开（公告）日：2006-08-10

  Trans-9,cis-11-octadecadienoic acid is produced by forming a urea inclusion complex with cis-linoleic acid, treating the complex with a catalytic amount of a base, and recovering the trans-9,cis-11 octadecadienoic acid. Tans-10,cis-12-octadecadienoic acid is produced by iodinating cis-linoleic acid at temperatures of about −5-20° C. A mixture of trans-9,cis-11 octadecadienoic acid and trans-10,cis-12-octadecadienoic acid comprising is produced by iodinating cis-linoleic acid at temperatures ranging from about 50 to about 90° C.

  通过与顺式亚麻酸形成脲包合物，用催化剂量的碱处理该复合物，并回收反式-9，顺式-11-十八碳二烯酸来生产反式-9，顺式-11-十八碳二烯酸。在约-5-20°C的温度下，通过对顺式亚麻酸进行碘化来生产反式-10，顺式-12-十八碳二烯酸。在约50到约90°C的温度范围内，通过对顺式亚麻酸进行碘化来生产反式-9，顺式-11-十八碳二烯酸和反式-10，顺式-12-十八碳二烯酸的混合物。
• Functional acylglycerides
  申请人：Natural ASA

  公开号：US20030144353A1

  公开（公告）日：2003-07-31

  The present invention relates to the field of human and animal nutrition, and in particular to certain novel compositions of conjugated linoleic acids (CLA). In particular, the present invention relates certain isomers of conjugated linoleic acids at either the SN1 and SN3 or SN2 positions of the acylglyceride molecule and another fatty acyl residue at the other of the SN1 and SN3 or SN2 positions of the acylglyceride molecule. These novel acylglyceride compositions containing conjugated linoleic acyl residues, medium chain fatty acyl residues, long chain fatty acyl residues, and &ohgr;3, &ohgr;6, and &ohgr;9 fatty acyl residues are efficacious as pharmaceutical compositions, animal feed additives, and human dietary supplements.

  本发明涉及人类和动物营养领域，特别是某些共轭亚油酸（CLA）的新型组合物。具体而言，本发明涉及在酰基甘油分子的SN1和SN3或SN2位置上的某些共轭亚油酸异构体以及在酰基甘油分子的SN1和SN3或SN2位置上的另一种脂肪酰残基。这些新型酰基甘油组成物包含共轭亚油酸酰残基、中链脂肪酰残基、长链脂肪酰残基和&ohgr;3、&ohgr;6和&ohgr;9脂肪酰残基，可作为制药组合物、动物饲料添加剂和人类膳食补充剂。
• CONJUGATED LINOLEIC ACID COMPOSITIONS
  申请人：Natural ASA

  公开号：US20040058998A1

  公开（公告）日：2004-03-25

  The present invention relates to the manufacture of conjugated linoleic acid, and in particular, to dietary supplements, feeds and food products containing conjugated linoleic acid. Accordingly, processes for producing conjugated linoleic acid of high purity and acid value are disclosed. These processes utilize alcoholate catalysts and esters of sunflower oil, safflower oil, or corn oil as the source of linoleic acid. The esters of conjugated linoleic acid produced by the process can be used in animal feeds and in food products suitable for human consumption. Furthermore, the esters can be converted into free fatty acids or incorporated into triglycerides.

  本发明涉及共轭亚油酸的制造，特别是涉及含有共轭亚油酸的膳食补充剂、饲料和食品产品。因此，本发明揭示了生产高纯度和酸值的共轭亚油酸的过程。这些过程利用醇酸催化剂和葵花籽油、红花籽油或玉米油的酯作为亚油酸的来源。该过程生产的共轭亚油酸酯可以用于动物饲料和适合人类食用的食品产品中。此外，酯可以转化为游离脂肪酸或并入甘油酯中。