H-Glu-Lys-Pro-OH

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: H-Glu-Lys-Pro-OH
• 英文别名: (2S)-1-[(2S)-6-amino-2-[[(2S)-2-amino-4-carboxybutanoyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
• 化学式: C₁₆H₂₈N₄O₆
• 分子量: 372.42
• InChiKey: FMBWLLMUPXTXFC-SRVKXCTJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -7.3
• 重原子数：
  26
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  176
• 氢给体数：
  5
• 氢受体数：
  8

文献信息

• [EN] NOVEL PEPTIDES WITH ANTI-HYPERTENSIVE ACTIVITY<br/>[FR] NOUVEAUX PEPTIDES A ACTIVITE HYPOTENSIVE
  申请人：MONSANTO CO

  公开号：WO2001068114A1

  公开（公告）日：2001-09-20

  Provided are novel tri-peptides which exhibit anti-hypertensive activity. These anti-hypertensive peptides may be used as active ingredients in pharmaceutical compositions, dietary supplements and food ingredients. The present invention also relates to using such novel anti-hypertensive peptides for methods of treatment and prophylaxis of primary hypertension as well as hypertension associated with myocardial infarction, left ventricular systolic dysfunction, diabetes mellitus, progressive renal failure and congestive heart failure.