异戊基丙基硫醚 | 28914-23-0

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 中文名称: 异戊基丙基硫醚
• 英文名称: isopentyl-propyl sulfide
• 英文别名: Propylisoamylsulfid；Isopentyl-propyl-sulfid；7-Methyl-4-thiaoctane；3-methyl-1-propylsulfanylbutane
• CAS: 28914-23-0
• 化学式: C₈H₁₈S
• 分子量: 146.297
• InChiKey: NZPWRMRDLFXMPA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  9
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  isopentylsulfanyl cyanate 、 丙基溴化镁 在 乙醚 作用下， 生成 异戊基丙基硫醚 、 异戊硫醇
  参考文献：
  名称：

  Adams; Bramlet; Tendick, Journal of the American Chemical Society, 1920, vol. 42, p. 2374

  摘要：

  DOI：

文献信息

• THERAPEUTIC SUBSTITUTED PYRROLES
  申请人：Old David W.

  公开号：US20100048664A1

  公开（公告）日：2010-02-25

  Disclosed herein is a compound represented by a formula: Therapeutic methods, compositions, and medicaments related thereto are also disclosed.

  本公开的是一种由以下化学式表示的化合物：还公开了与之相关的治疗方法、组合物和药物。
• AMINOALCOHOL LIPIDOIDS AND USES THEREOF
  申请人：Mahon Kerry Peter

  公开号：US20100331234A1

  公开（公告）日：2010-12-30

  Aminoalcohol lipidoids are prepared by reacting an amine with an epoxide-terminated compound are described. Methods of preparing aminoalcohol lipidoids from commercially available starting materials are also provided. Aminoalcohol lipidoids may be prepared from racemic or stereochemically pure epoxides. Aminoalcohol lipidoids or salts forms thereof are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the amino moiety of these aminoalcohol lipidoid compounds, they are particularly suited for the delivery of polynucleotides. Complexes, micelles, liposomes or particles containing the inventive lipidoids and polynucleotide have been prepared. The inventive lipidoids may also be used in preparing microparticles for drug delivery. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings.

  本文介绍了通过将胺与环氧末端化合物反应制备氨基醇脂质体的方法。还提供了从商业起始材料制备氨基醇脂质体的方法。氨基醇脂质体可以从外消旋或立体化学纯的环氧化合物制备。氨基醇脂质体或其盐形式最好是可生物降解和生物相容的，并可用于各种药物递送系统。由于这些氨基醇脂质体化合物的氨基基团，它们特别适用于多核苷酸的递送。已制备包含发明性脂质体和多核苷酸的复合物、胶束、脂质体或颗粒。发明性脂质体还可用于制备药物递送的微粒。鉴于它们缓冲其周围环境pH值的能力，它们特别适用于递送不稳定的药物。
• PROCESS FOR PREPARATION OF ALKYL SULFONE COMPOUNDS
  申请人：Sumitomo Seika Chemicals Co. Ltd.

  公开号：EP2441751A1

  公开（公告）日：2012-04-18

  An object of the present invention is to provide a method for preparation of an alkyl sulfone compound simply and safely with high yield, and an alkyl sulfone compound. The present invention is a method for preparing an alkyl sulfone compound represented by formula (2), comprising: oxidizing an alkyl sulfide compound represented by formula (1) using an oxidizing agent in the presence of a tungstate catalyst: in formula (1), R1 represents a C1-C3 alkyl group, and R2 represents a C3-C5 alkyl group, in formula (2), R1 and R2 are the same alkyl groups as R1 and R2 in formula (1), respectively.

  本发明的目的是提供一种简单、安全、高产率地制备烷基砜化合物和烷基砜化合物的方法。 本发明是一种制备由式（2）表示的烷基砜化合物的方法，包括 在钨酸盐催化剂存在下，使用氧化剂氧化式（1）代表的烷基砜化合物： 式（1）中，R1 代表 C1-C3 烷基，R2 代表 C3-C5 烷基、 在式 (2) 中，R1 和 R2 分别是与式 (1) 中的 R1 和 R2 相同的烷基。
• PROCESS FOR PRODUCING POLYDIENES
  申请人：Bridgestone Corporation

  公开号：EP2825574B1

  公开（公告）日：2016-02-24
• Amine-containing lipids and uses thereof
  申请人：Anderson Daniel G.

  公开号：US20110009641A1

  公开（公告）日：2011-01-13

  Nitrogen-containing lipids prepared from the conjugate addition of amines to acrylates, acrylamides, or other carbon-carbon double bonds conjugated to electron-withdrawing groups are described. Methods of preparing these lipids from commercially available starting materials are also provided. These amine-containing lipids or salts forms of these lipids are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the amino moiety of these lipids, they are particularly suited for the delivery of polynucleotides. Complexes or nanoparticles containing the inventive lipid and polynucleotide have been prepared. The inventive lipids may also be used to in preparing microparticle for drug delivery. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings.