3-(Diaminomethylidene)-1,1-dimethylguanidine;5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydrochloride

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 3-(Diaminomethylidene)-1,1-dimethylguanidine;5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydrochloride
• 化学式: C23H32ClN7O3S
• 分子量: 522.1
• InChiKey: YYJYMMGGWNYEDQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.34
• 重原子数：
  35
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  185
• 氢给体数：
  5
• 氢受体数：
  6

文献信息

• MEDICAMENT
  申请人：SCHRAMM GEORG

  公开号：US20090118245A1

  公开（公告）日：2009-05-07

  The present invention relates to a medicament which contains as the active ingredient combination at least one gestagen with a contraceptive action as the sole hormone component and at least one insulin sensitiser, which medicament is in particular suitable for preventing or treating pathological disorders which are caused by polycystic ovary syndrome (PCOS).